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CA9 抗体 (AA 37-186)

CA9 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7C4A5 unconjugated
产品编号 ABIN1724883
发货至: 中国
  • 抗原 See all CA9 抗体
    CA9 (Carbonic Anhydrase IX (CA9))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 37-186
    适用
    • 90
    • 28
    • 24
    • 14
    • 7
    • 5
    • 5
    宿主
    • 76
    • 33
    小鼠
    克隆类型
    • 64
    • 45
    单克隆
    标记
    • 52
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CA9 antibody is un-conjugated
    应用范围
    • 74
    • 28
    • 27
    • 27
    • 25
    • 14
    • 13
    • 11
    • 10
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. coli.
    克隆位点
    7C4A5
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Neumeister, Sullivan, Lindner, Lezon-Geyda, Li, Zavada, Martel, Glazer, Tuck, Rimm, Harris: "Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer." in: Breast cancer research and treatment, Vol. 136, Issue 1, pp. 67-75, (2012) (PubMed).

    Pinheiro, Sousa, Albergaria, Paredes, Dufloth, Vieira, Schmitt, Baltazar: "GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression." in: Histology and histopathology, Vol. 26, Issue 10, pp. 1279-86, (2011) (PubMed).

  • 抗原
    CA9 (Carbonic Anhydrase IX (CA9))
    别名
    CA9 (CA9 产品)
    别名
    CA9 antibody, CAIX antibody, Ca9 antibody, MN/CA9 antibody, MN antibody, carbonic anhydrase 9 antibody, CA9 antibody, CAH9 antibody, Car9 antibody
    背景

    Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. ,

    Aliases: MN, CAIX

    分子量
    49.7 kDa
    基因ID
    768
    HGNC
    768
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