PTK2B 抗体 (AA 815-997)
(3 references)-
- 抗原 See all PTK2B 抗体
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
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抗原表位
- AA 815-997
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PTK2B antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of PYK2 (aa815-997) expressed in E. coli.
- 克隆位点
- 5E2D5
- 亚型
- IgG2a
- Top Product
- Discover our top product PTK2B Primary Antibody
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anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibody
PTK2B 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 1-1009) antibodyPTK2B 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibodyPTK2B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (pTyr402) antibodyPTK2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 805-838), (C-Term) antibodyPTK2B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB50594 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) antibodyPTK2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 682-871) antibodyPTK2B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal X1 unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 812-861) antibodyPTK2B 适用: 人, 小鼠, 大鼠, 犬, 兔, Pig, 马, 猴, Cow, 豚鼠, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (Tyr579) antibodyPTK2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PTK2B Protein tyrosine Kinase 2 beta (PTK2B) (AA 707-875) antibodyPTK2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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: "Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products." in: Experimental hematology, Vol. 32, Issue 4, pp. 365-74, (2004) (PubMed).
: "Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites." in: Journal of cell science, Vol. 117, Issue Pt 12, pp. 2557-68, (2004) (PubMed).
: "Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma." in: International journal of cancer. Journal international du cancer, Vol. 113, Issue 5, pp. 689-98, (2004) (PubMed).
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: "Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products." in: Experimental hematology, Vol. 32, Issue 4, pp. 365-74, (2004) (PubMed).
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- 抗原
- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
- 别名
- PYK2 (PTK2B 产品)
- 背景
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Description: PYK2: PTK2B protein tyrosine kinase 2 beta, also known as PTK2B, PKB, PTK, CAKB, FAK2, FRNK. Entrez Protein NP_004094. It is a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.
Aliases: PKB, PTK, CAKB, FAK2, FRNK, PTK2B
- 分子量
- 115.8 kDa
- 基因ID
- 2185
- NCBI登录号
- NP_004094
- HGNC
- 2185
- 途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
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