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Aurora Kinase B 抗体

AURKB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 13E8D3 unconjugated
产品编号 ABIN1724660
发货至: 中国
  • 抗原 See all Aurora Kinase B (AURKB) 抗体
    Aurora Kinase B (AURKB)
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Aurora Kinase B antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of AURKB expressed in E. coli.
    克隆位点
    13E8D3
    亚型
    IgG1
    Top Product
    Discover our top product AURKB Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Song, So, Cheng, Tang, Croft: "Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion." in: Immunity, Vol. 22, Issue 5, pp. 621-31, (2005) (PubMed).

    Kapoor, Lavoie, Frappier: "EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases." in: Molecular and cellular biology, Vol. 25, Issue 12, pp. 4934-45, (2005) (PubMed).

  • 抗原
    Aurora Kinase B (AURKB)
    别名
    AURKB (AURKB 产品)
    背景

    Description: AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases

    Aliases: AURKB

    基因ID
    9212
    HGNC
    9212
    途径
    TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
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