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RPSA/Laminin Receptor 抗体

RPSA 适用: 人, 大鼠 WB, IHC (p), IF (p) 宿主: 小鼠 Monoclonal 5D4 unconjugated
产品编号 ABIN1713335
发货至: 中国
  • 抗原 See all RPSA/Laminin Receptor (RPSA) 抗体
    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
    适用
    • 55
    • 31
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    人, 大鼠
    宿主
    • 46
    • 10
    小鼠
    克隆类型
    • 35
    • 20
    单克隆
    标记
    • 36
    • 4
    • 2
    • 2
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    This RPSA/Laminin Receptor antibody is un-conjugated
    应用范围
    • 35
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    • 9
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    • 3
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    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 大鼠
    纯化方法
    Purified by Protein G.
    免疫原
    KLH conjugated synthetic peptide derived from middle of human LAMR1
    克隆位点
    5D4
    亚型
    IgG
    Top Product
    Discover our top product RPSA Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Wang, Yu, Guan, Liu, Qiao: "67-kDa Laminin receptor contributes to hypoxia-induced migration and invasion of trophoblast-like cells by mediating matrix metalloproteinase-9." in: Clinical and experimental pharmacology & physiology, Vol. 42, Issue 5, pp. 549-58, (2015) (PubMed).

  • 抗原
    RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))
    别名
    LAMR1 (RPSA 产品)
    别名
    37LRP antibody, 67LR antibody, LBP/p40 antibody, LRP/LR antibody, LamR antibody, rpsa antibody, LamR1 antibody, RPSA antibody, LAMBR antibody, LAMR1 antibody, LBP antibody, LRP antibody, NEM/1CHD4 antibody, SA antibody, lamR antibody, p40 antibody, 67kDa antibody, 67lr antibody, AL022858 antibody, Lamr antibody, Lamr1 antibody, Lamrl1 antibody, MLR antibody, P40 antibody, P40-3 antibody, P40-8 antibody, lamr1 antibody, zgc:55831 antibody, zgc:77824 antibody, DMRT1 antibody, 40S ribosomal protein SA antibody, 67kD laminin receptor antibody, ribosomal protein SA antibody, rssa antibody, rpsa antibody, RPSA antibody, Rpsa antibody, LOC100144340 antibody
    背景

    Synonyms: 37LRP, P37- kDa laminin receptor precursor, MGr1-Ag, laminin receptor 1, 67kD, ribosomal protein SA, 34/67 kDa laminin receptor, 40S ribosomal protein SA, 67LR, Colon carcinoma laminin-binding protein, LAMBR, Laminin Receptor 1, LAMR 1, LAMR1, LRP, Multidrug resistance-associated protein MGr1-Ag, NEM/1CHD4, p40, Ribosomal Protein SA, RPSA, 67kD laminin receptor.

    Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

    基因ID
    3921
    途径
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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