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SYPL1 抗体 (AA 121-220) (HRP)

SYPL1 适用: 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1712563
发货至: 中国
  • 抗原 See all SYPL1 products
    SYPL1 (Synaptophysin-Like 1 (SYPL1))
    抗原表位
    • 14
    • 10
    • 8
    • 6
    • 2
    AA 121-220
    适用
    • 20
    • 18
    • 4
    • 2
    • 2
    • 2
    • 1
    小鼠
    宿主
    • 35
    克隆类型
    • 35
    多克隆
    标记
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYPL1 antibody is conjugated to HRP
    应用范围
    • 34
    • 15
    • 14
    • 13
    • 13
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Pantophysin
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SYPL1 (Synaptophysin-Like 1 (SYPL1))
    别名
    Pantophysin (SYPL1 产品)
    别名
    Sypl antibody, H-SP1 antibody, SYPL antibody, AI314763 antibody, AI604763 antibody, D12Ertd446e antibody, PanI antibody, Pphn antibody, Sypl1 antibody, synaptophysin like 1 antibody, synaptophysin-like 1 antibody, synaptophysin-like protein antibody, SYPL1 antibody, Sypl1 antibody, Sypl antibody
    背景

    Synonyms: SYPL1_HUMAN, Synaptophysin-like protein 1, Pantophysin, SYPL1, H-SP1, SYPL.

    Background: The MARVEL domain is a 130 amino acid motif that contains four transmembrane helices, both of which have cytoplasmic N- and C-terminal regions. MARVEL domain-containing proteins are thought to participate in tight junction regulation, the biogenesis of vesicular transport carriers and in cholesterol-rich membrane apposition events. Pantophysin, also known as SYPL1 (synaptophysin-like protein 1) or H-SP1, is a 259 amino acid multi-pass membrane protein that localizes to melanosomes and vesicles, as well as to the cytoplasm, and contains one MARVEL domain. Expressed as multiple alternatively spliced isoforms, pantophysin is present in tissues throughout the body where it may play a role in vesicle trafficking and protein transport. The gene encoding pantophysin maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

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