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GOT1L1 抗体 (AA 201-300) (HRP)

GOT1L1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1712548
发货至: 中国
  • 抗原 See all GOT1L1 products
    GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
    抗原表位
    • 14
    • 8
    • 8
    • 7
    AA 201-300
    适用
    • 29
    • 14
    • 4
    小鼠, 大鼠
    宿主
    • 30
    克隆类型
    • 30
    多克隆
    标记
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GOT1L1 antibody is conjugated to HRP
    应用范围
    • 29
    • 14
    • 14
    • 13
    • 13
    • 13
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GOT1L1
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GOT1L1 (Glutamic-Oxaloacetic Transaminase 1-Like 1 (GOT1L1))
    别名
    GOT1L1 (GOT1L1 产品)
    别名
    1700083M11Rik antibody, RGD1307172 antibody, glutamic-oxaloacetic transaminase 1 like 1 antibody, glutamic-oxaloacetic transaminase 1-like 1 antibody, GOT1L1 antibody, Got1l1 antibody
    背景

    Synonyms: AATC2_HUMAN, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Glutamic oxaloacetic transaminase 1 like 1, GOT1L1, Putative aspartate aminotransferase, Putative aspartate aminotransferase, cytoplasmic 2, Transaminase A-like protein 1.

    Background: GOT1L1, Glutamate oxaloacetate transaminase 1-like protein 1, is a 421 amino acid member of the class-I pyridoxal-phosphate-dependent aminotransferase family. Similar to glutamate-oxaloacetate transaminase (GOT1), GOT1L1 is found primarily as a homodimer in the cytoplasmic space but also has mitochondrial and chloroplastic isozymes. GOT1L1 transaminates 2-oxoglutarate with L-aspartate to yield oxaloacetate and L-glutamate. This reaction requires a pyridoxal phosphate cofactor to occur. The GOT1L1 peptidase is predominately expressed in the liver and serum levels of this protein can be used as an indicator of liver disease. Also, elevated glutamate concentrations in the brain interstitial fluids can lead to pathological brain conditions. The glutamate-scavenging properties of these aminotranferase type enzymes likely prevent glutamate excitotoxicity and the long-lasting neurological deficits seen after stroke.

    基因ID
    137362
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