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FGFR1 抗体 (pTyr154) (HRP)

FGFR1 适用: 人 ELISA, IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1712440
发货至: 中国
  • 抗原 See all FGFR1 抗体
    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
    抗原表位
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    pTyr154
    适用
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    宿主
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    克隆类型
    • 230
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    多克隆
    标记
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    This FGFR1 antibody is conjugated to HRP
    应用范围
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    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr154
    亚型
    IgG
    Top Product
    Discover our top product FGFR1 Primary Antibody
  • 应用备注
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
    别名
    FGFR1 (FGFR1 产品)
    别名
    FGFR antibody, fgfr antibody, X1FGFR antibody, XFGFR-1 antibody, XFGFRA2 antibody, bfgfr antibody, cek antibody, fgfr1 antibody, flg antibody, flt-2 antibody, flt2 antibody, kal2 antibody, ogd antibody, xfgfr1 antibody, CG7223 antibody, CT22273 antibody, CT39172 antibody, DFGF-R1 antibody, DFGF-R2 antibody, DFR-1 antibody, DFR1 antibody, DFR1/DFGF-R2 antibody, DPR3 antibody, DTRK(FR1) antibody, Dfr-1 antibody, Dfr1 antibody, DmHD-38 antibody, Dmel\\CG7223 antibody, Dtk1 antibody, EMS2 antibody, FGF-R2 antibody, FGFR2 antibody, FR1 antibody, Fr1 antibody, HD-38 antibody, HTL/FGFR1 antibody, Htl antibody, Tk1 antibody, dtk1 antibody, i100 antibody, i150 antibody, i79 antibody, j372 antibody, cd331 antibody, fgfbr antibody, fgfr-1 antibody, hbgfr antibody, n-sam antibody, ach antibody, cd333 antibody, cek2 antibody, fgfr-3 antibody, hsfgfr3ex antibody, jtk4 antibody, BFGFR antibody, CD331 antibody, CEK antibody, FGFBR antibody, FGFR-1 antibody, FLG antibody, FLT-2 antibody, FLT2 antibody, HBGFR antibody, HH2 antibody, KAL2 antibody, N-SAM antibody, OGD antibody, bFGF-R-1 antibody, AW208770 antibody, Eask antibody, Fgfr-1 antibody, Flt-2 antibody, Hspy antibody, FLG-1 antibody, FGFRI antibody, x1fgfr antibody, cb231 antibody, sb:cb231 antibody, fibroblast growth factor receptor antibody, fibroblast growth factor receptor 1 S homeolog antibody, basic fibroblast growth factor receptor 1 antibody, heartless antibody, fibroblast growth factor receptor 1 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog antibody, Fibroblast growth factor receptor 1 antibody, fibroblast growth factor receptor 1 L homeolog antibody, fibroblast growth factor receptor 1a antibody, FGFR antibody, fgfr antibody, fgfr1.S antibody, CpipJ_CPIJ005849 antibody, htl antibody, fgfr1 antibody, fgfr3.L antibody, FGFR1 antibody, Fgfr1 antibody, fgfr1.L antibody, fgfr1a antibody
    背景

    Synonyms: FGFR1 phospho Y154, FGFR1 phospho Tyr154, p-FGFR1 phospho Y154, bFGF R, BFGFR, C FGR, CD 331, CD331, CD331 antigen, CEK, FGFBR, FGFR 1, Fibroblast growth factor receptor 1, FLG, FLG protein, FLJ14326, FLT 2, FLT2, Fms like tyrosine kinase 2, Fms related tyrosine kinase 2, Fms related tyrosine kinase 2 Pfefer syndrome, H2, H3, H4, H5, HBGFR, Heparin binding growth factor receptor, Hydroxyaryl protein kinase, KAL 2, KAL2, MFR, N SAM, N sam tyrosine kinase, Protein tyrosine kinase, Tyrosylprotein kinase, Basic fibroblast growth factor receptor 1, FGFR1_HUMAN.

    Background: Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through the cellular surface tyrosine kinase receptors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane region and a cytoplasmic kinase domain (1). Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues (2). Seven tyrosine residues in the cytoplasmic tail of FGFR-1 can be phosphorylated: Tyr463, Tyr583, Tyr585, Tyr653, Tyr654, Tyr730 and Tyr766. Tyrosine 653 and 654 are important for catalytic activity of the activated FGFR and are essential for signaling (3). The other phosphorylated tyrosine residues may provide docking sites for downstream signaling components such as Crk and PLCgamma.

    基因ID
    2260
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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