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NAE1 抗体 (AA 401-500) (HRP)

NAE1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1712107
发货至: 中国
  • 抗原 See all NAE1 抗体
    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
    抗原表位
    • 14
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    适用
    • 57
    • 24
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 63
    • 8
    克隆类型
    • 65
    • 6
    多克隆
    标记
    • 31
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAE1 antibody is conjugated to HRP
    应用范围
    • 64
    • 34
    • 29
    • 13
    • 13
    • 9
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human APPBP1
    亚型
    IgG
    Top Product
    Discover our top product NAE1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
    别名
    APPBP1 (NAE1 产品)
    别名
    APPBP1 antibody, CG7828 antibody, Dmel\\CG7828 antibody, anon-WO0140519.225 antibody, dAPP-BP1 antibody, dAPPBP1 antibody, A-116A10.1 antibody, ula-1 antibody, Appbp1 antibody, 59kDa antibody, appbp1 antibody, zgc:66148 antibody, beta-Amyloid precursor protein binding protein 1 antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit 1 S homeolog antibody, nedd8 activating enzyme E1 subunit 1 antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, APP-BP1 antibody, NAE1 antibody, Nae1 antibody, nae1.S antibody, nae1 antibody, ula-1 antibody
    背景

    Synonyms: HPP1, ula-1, APPBP1, A-116A10.1, NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1

    Background: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.

    基因ID
    8883
    UniProt
    Q13564
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