(6 references)-
- 抗原 See all LAIR1 抗体
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LAIR1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody NKTA255 recognizes an extracellular epitope of CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Activated NK cells and CD3- thymocytes
- 克隆位点
- NKTA255
- 亚型
- IgG1
- Top Product
- Discover our top product LAIR1 Primary Antibody
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anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) antibody
LAIR1 适用: 人 WB, FACS, IP 宿主: 小鼠 Monoclonal NKTA255 unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 103-203) antibodyLAIR1 适用: 人 WB, ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 1E8D4 unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 22-165) antibodyLAIR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 1-287) antibodyLAIR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 1-287) antibodyLAIR1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3B2 unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 188-287) antibodyLAIR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G4 unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) antibody (APC)LAIR1 适用: 人 FACS 宿主: 小鼠 Monoclonal NKTA255 APC
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (Internal Region) antibodyLAIR1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (Internal Region) antibodyVerified LAIR1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 187-287) antibodyLAIR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 溶解方式
- No reconstitution is necessary.
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
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Do not freeze.
Avoid prolonged exposure to light. - 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients." in: PLoS ONE, Vol. 7, Issue 2, pp. e31903, (2012) (PubMed).
: "C1q limits dendritic cell differentiation and activation by engaging LAIR-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 46, pp. E3160-7, (2012) (PubMed).
: "The inhibitory collagen receptor LAIR-1 (CD305)." in: Journal of leukocyte biology, Vol. 83, Issue 4, pp. 799-803, (2008) (PubMed).
: "The Eighth Human Leucocyte Differentiation Antigen (HLDA8) Workshop: natural killer cell section report." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 17-20, (2005) (PubMed).
: "p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor." in: European journal of immunology, Vol. 28, Issue 7, pp. 2086-91, (1998) (PubMed).
: "p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes." in: International immunology, Vol. 9, Issue 9, pp. 1271-9, (1997) (PubMed).
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: "Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients." in: PLoS ONE, Vol. 7, Issue 2, pp. e31903, (2012) (PubMed).
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- 抗原
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
- 别名
- CD305 / LAIR1 (LAIR1 产品)
- 别名
- 5133400O11Rik antibody, BB115266 antibody, D7Bwg0421e antibody, Lair-1 antibody, mLair-1 antibody, CD305 antibody, LAIR-1 antibody, leukocyte-associated Ig-like receptor 1 antibody, leukocyte associated immunoglobulin like receptor 1 antibody, leukocyte-associated immunoglobulin-like receptor 1 antibody, Lair1 antibody, LAIR1 antibody
- 背景
- Leukocyte associated immunoglobulin like receptor,CD305, also known as LAIR1 (leukocyte-associated Ig-like receptor 1), is an inhibitory receptor found on many types of peripheral blood cells. It serves to suppress cell cytotoxicity, activation, proliferation, and differentiation regarding autoantigens via its two intracellular ITIM sites. CD305 belongs to the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family of proteins. It reacts with collagen ligands.,LAIR1
- 基因ID
- 3903
- UniProt
- Q6GTX8
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