电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

LAIR1 抗体

LAIR1 适用: 人 WB, FACS, IP 宿主: 小鼠 Monoclonal NKTA255 unconjugated
产品编号 ABIN1690731
发货至: 中国
  • 抗原 See all LAIR1 抗体
    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
    适用
    • 53
    • 11
    • 1
    宿主
    • 38
    • 14
    • 1
    小鼠
    克隆类型
    • 41
    • 12
    单克隆
    标记
    • 25
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAIR1 antibody is un-conjugated
    应用范围
    • 36
    • 25
    • 9
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
    特异性
    The mouse monoclonal antibody NKTA255 recognizes an extracellular epitope of CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Activated NK cells and CD3- thymocytes
    克隆位点
    NKTA255
    亚型
    IgG1
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Colombo, Canevali, Magnani, Rossi, Puppo, Zocchi, Poggi: "Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients." in: PLoS ONE, Vol. 7, Issue 2, pp. e31903, (2012) (PubMed).

    Son, Santiago-Schwarz, Al-Abed, Diamond: "C1q limits dendritic cell differentiation and activation by engaging LAIR-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 46, pp. E3160-7, (2012) (PubMed).

    Meyaard: "The inhibitory collagen receptor LAIR-1 (CD305)." in: Journal of leukocyte biology, Vol. 83, Issue 4, pp. 799-803, (2008) (PubMed).

    Warren: "The Eighth Human Leucocyte Differentiation Antigen (HLDA8) Workshop: natural killer cell section report." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 17-20, (2005) (PubMed).

    Poggi, Tomasello, Ferrero, Zocchi, Moretta: "p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor." in: European journal of immunology, Vol. 28, Issue 7, pp. 2086-91, (1998) (PubMed).

    Poggi, Tomasello, Revello, Nanni, Costa, Moretta: "p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes." in: International immunology, Vol. 9, Issue 9, pp. 1271-9, (1997) (PubMed).

  • 抗原
    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
    别名
    CD305 / LAIR1 (LAIR1 产品)
    别名
    5133400O11Rik antibody, BB115266 antibody, D7Bwg0421e antibody, Lair-1 antibody, mLair-1 antibody, CD305 antibody, LAIR-1 antibody, leukocyte-associated Ig-like receptor 1 antibody, leukocyte associated immunoglobulin like receptor 1 antibody, leukocyte-associated immunoglobulin-like receptor 1 antibody, Lair1 antibody, LAIR1 antibody
    背景
    Leukocyte associated immunoglobulin like receptor,CD305, also known as LAIR1 (leukocyte-associated Ig-like receptor 1), is an inhibitory receptor found on many types of peripheral blood cells. It serves to suppress cell cytotoxicity, activation, proliferation, and differentiation regarding autoantigens via its two intracellular ITIM sites. CD305 belongs to the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family of proteins. It reacts with collagen ligands.,LAIR1
    基因ID
    3903
    UniProt
    Q6GTX8
You are here:
客服