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VEGFR2/CD309 抗体 (Extracellular Domain) (Biotin)

Name: VEGFR2/CD309 抗体 (Extracellular Domain) (Biotin)
SKU: ABIN155183
Availability: OutOfStock

VEGFR2 适用: 人 WB, IP, EIA, Func 宿主: 兔 Polyclonal Biotin

产品编号 ABIN155183

发货至: 中国

Datasheet as PDF

抗原 See all VEGFR2/CD309 (VEGFR2) 抗体

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
抗原表位
37

36

26

22

20

20

16

16

14

10

9

8

8

6

6

6

6

5

5

5

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain
适用
305

196

145

18

9

7

4

3

3

3

2

1

1

1

1

1

1

1

1

1
人
宿主
306

49

9

2

1

1

1
兔
Compatible Secondaries
克隆类型
301

68
多克隆
标记
162

33

21

15

13

13

11

11

11

11

11

11

6

6

6

6

6

2

2

2

2

1

1

1

1

1

1

1

1
This VEGFR2/CD309 antibody is conjugated to Biotin
应用范围
236

136

98

81

63

34

26

24

21

13

13

12

8

7

7

3

3

2

1
Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Functional Studies (Func)

特异性

The antibody will detect native and recombinant VEGFR-2/KDR.

纯化方法

Antigenaffinity chromatography with immobilised recombinant soluble VEGFR-2/KDR

免疫原

Highly pure recombinant human soluble extracellular domain of KDR (110 kDa)

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应用备注

ELISA: 5-15 μg/mL. Western blot. Immunoprecipitation. Neutralizing experiments.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
溶解方式

Reconstitute in sterile water to a concentration of 0.1 mg/mL.

缓冲液

PBS pH 7.4 w/o preservative and stabilizer

注意事项

Do Not Add Sodium Azide

注意事项

Dilute only prior to immediate use. Avoid cycles of freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store vial at 2-8 °C prior to restoration. For extended storage reconstitute product with 50% glycerol instead of water and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.
抗原

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

别名

CD309 / VEGFR-2 / Flk-1 (VEGFR2 产品)

别名

CD309 antibody, FLK1 antibody, VEGFR antibody, VEGFR2 antibody, 6130401C07 antibody, Flk-1 antibody, Flk1 antibody, Krd-1 antibody, Ly73 antibody, VEGFR-2 antibody, sVEGFR-2 antibody, Vegfr-2 antibody, FLK-1 antibody, flk-1 antibody, vegfr-2 antibody, KDR antibody, FLK/KDR antibody, flk1 antibody, flk1b antibody, kdrb antibody, si:busm1-205d10.1 antibody, si:ch211-254j6.1 antibody, si:ch211-278f21.4 antibody, wu:fc31a09 antibody, fk52c05 antibody, flk antibody, kdr antibody, kdra antibody, vegfr2 antibody, vegfr4 antibody, vegr2 antibody, wu:fk52c05 antibody, kinase insert domain receptor antibody, kinase insert domain protein receptor antibody, vascular endothelial growth factor receptor kdr-like antibody, kinase insert domain receptor (a type III receptor tyrosine kinase) antibody, kinase insert domain receptor like antibody, KDR antibody, Kdr antibody, LOC100136647 antibody, kdr antibody, kdrl antibody

背景

VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2

基因ID

3791

NCBI登录号

NP_002244

UniProt

P35968

途径

RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling