This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TRPC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 834-862 amino acids from the C-terminal region of human TRPC7.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.