This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This TREML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-241 amino acids from the C-terminal region of human TREML1.
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11, MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956], Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM].