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TOX 抗体 (N-Term)

TOX 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449998
发货至: 中国
  • 抗原 See all TOX 抗体
    TOX (Thymus High Mobility Group Box Protein (TOX))
    抗原表位
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 16
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 17
    克隆类型
    • 16
    • 1
    多克隆
    标记
    • 13
    • 2
    • 1
    • 1
    This TOX antibody is un-conjugated
    应用范围
    • 11
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    A 17 amino acid synthetic peptide near the amino terminus of Human TOX
    亚型
    IgG
    Top Product
    Discover our top product TOX Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    TOX (Thymus High Mobility Group Box Protein (TOX))
    别名
    TOX (TOX 产品)
    别名
    TOX1 antibody, 1700007F02Rik antibody, thymocyte selection associated high mobility group box antibody, thymocyte selection-associated high mobility group box antibody, TOX antibody, Tox antibody
    背景
    TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development (1,2). It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.Synonyms: KIAA0808, Thymocyte selection-associated high mobility group box protein TOX, Thymus high mobility group box protein TOX
    分子量
    58 kDa
    基因ID
    9760
    NCBI登录号
    NP_055544
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