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ATG2B 抗体 (N-Term)

ATG2B 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449993
发货至: 中国
  • 抗原 See all ATG2B products
    ATG2B (Autophagy Related 2B (ATG2B))
    抗原表位
    • 14
    • 10
    • 5
    • 1
    • 1
    • 1
    N-Term
    适用
    • 26
    • 10
    • 2
    宿主
    • 26
    克隆类型
    • 26
    多克隆
    标记
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    This ATG2B antibody is un-conjugated
    应用范围
    • 20
    • 16
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    A 19 amino acid synthetic peptide near the amino terminus of Human ATG2B
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ATG2B (Autophagy Related 2B (ATG2B))
    别名
    ATG2B (ATG2B 产品)
    别名
    C14orf103 antibody, 2410024A21Rik antibody, AI047755 antibody, AI503411 antibody, AW558123 antibody, C030004M05Rik antibody, C630028L02Rik antibody, mKIAA4067 antibody, autophagy related 2B antibody, ATG2B antibody, Atg2b antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.Synonyms: Autophagy related 2 homolog B
    分子量
    229 kDa
    基因ID
    55102
    NCBI登录号
    NP_060506
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