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ATG4D 抗体 (AA 227-257)

ATG4D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449634
发货至: 中国
  • 抗原 See all ATG4D 抗体
    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
    抗原表位
    • 15
    • 15
    • 13
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 227-257
    适用
    • 75
    • 40
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 92
    • 13
    • 1
    克隆类型
    • 93
    • 13
    多克隆
    标记
    • 29
    • 10
    • 9
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ATG4D antibody is un-conjugated
    应用范围
    • 93
    • 37
    • 35
    • 28
    • 26
    • 26
    • 15
    • 6
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
    免疫原
    KLH conjugated synthetic peptide between 227~257 amino acids from the Center of Human APG4D Genename: ATG4D
    亚型
    Ig Fraction
    Top Product
    Discover our top product ATG4D Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))
    别名
    APG4D / ATG4D (ATG4D 产品)
    别名
    APG4-D antibody, APG4D antibody, AUTL4 antibody, 9830134P12Rik antibody, Apg4d antibody, Atg4dl antibody, Autl4 antibody, apg4d antibody, autophagy related 4D cysteine peptidase antibody, autophagy related 4D, cysteine peptidase antibody, autophagy related 4D, cysteine peptidase L homeolog antibody, ATG4D antibody, Atg4d antibody, atg4d.L antibody
    背景
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.Synonyms: AUT-like 4 cysteine endopeptidase, AUTL4, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D
    分子量
    52922 Da
    基因ID
    84971
    NCBI登录号
    NP_116274
    途径
    Autophagy
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