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LC3B 抗体 (N-Term, pThr12)

MAP1LC3B 适用: 人 DB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449629
发货至: 中国
  • 抗原 See all LC3B (MAP1LC3B) 抗体
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    抗原表位
    • 23
    • 15
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    • 7
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    • 1
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    • 1
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    • 1
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    • 1
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    AA 1-30, N-Term, pThr12
    适用
    • 134
    • 51
    • 36
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 123
    • 14
    • 7
    克隆类型
    • 129
    • 16
    多克隆
    标记
    • 76
    • 14
    • 13
    • 10
    • 10
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LC3B antibody is un-conjugated
    应用范围
    • 89
    • 55
    • 52
    • 28
    • 24
    • 14
    • 13
    • 10
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Dot Blot (DB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (expected):Bovine.
    Species reactivity (tested):Human.
    纯化方法
    Protein A column, followed by two-step phosphospecific peptide affinity purification
    免疫原
    KLH conjugated synthetic phosphopeptide between 1~30 amino acids surrounding Thr12 of Human LC3
    亚型
    Ig Fraction
    Top Product
    Discover our top product MAP1LC3B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, 0.09 % (W/V) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
    别名
    LC3B (MAP1LC3B 产品)
    别名
    ATG8F antibody, LC3B antibody, MAP1A/1BLC3 antibody, MAP1LC3B-a antibody, Map1lc3 antibody, Mpl3 antibody, zbs559 antibody, 1010001C15Rik antibody, Atg8 antibody, LC3b antibody, zgc:56434 antibody, wu:fb60g11 antibody, map1lc3b antibody, MGC76283 antibody, MAP1LC3B antibody, microtubule associated protein 1 light chain 3 beta antibody, microtubule-associated protein 1 light chain 3 beta antibody, microtubule associated protein 1 light chain 3 beta L homeolog antibody, MAP1LC3B antibody, Map1lc3b antibody, map1lc3b antibody, map1lc3b.L antibody
    背景
    MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. These proteins are involved in formation of autophagosomal vacuoles (autophagosomes). MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3b is one of the light chain subunits and can associate with either MAP1A or MAP1B. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II. Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).Synonyms: Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B, MAP1A / 1B light chain 3 B, MAP1A/MAP1B, MAP1LC3B, Map1alc3, Map1lc3, Map1lc3b, Microtubule-associated protein 1 light chain 3 beta, Microtubule-associated proteins 1A/1B light chain 3B
    基因ID
    81631
    NCBI登录号
    NP_073729
    途径
    Autophagy
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