H5 antibody, h10 antibody, h1fv antibody, fb23b02 antibody, wu:fb23b02 antibody, zgc:65861 antibody, H1F0 antibody, H1fv antibody, H10 antibody, H1FV antibody, D130017D06Rik antibody, H1(0) antibody, h1(0)-1 antibody, h1f0 antibody, H1 antibody, H1 histone family member 0 antibody, H1 histone family, member 0 antibody, histone H1.0 antibody, H1 histone family member 0 S homeolog antibody, H1 histone family member 0 L homeolog antibody, histone I antibody, h1f0 antibody, H1F0 antibody, LOC698693 antibody, H1f0 antibody, h1f0.S antibody, h1f0.L antibody, his1 antibody
背景
The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. Histone H1, also known as linker histone, is bound to linker DNA region between nucleosomes, contributing to chromatin foldings in nucleus. It is known that histone H1 is also post-translationally modified, such as phosphorylation or methylation and relation of these modifications with biological meanings are under extensive investigations. Histone H1 is essential for higher order structure of mitotic chromosomes that are condensed structure of chromatin during mitosis.Synonyms: H1F0, H1FV, Histone H1', Histone H1(0)