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CD226 抗体 (FITC)

CD226 适用: 人 FACS 宿主: 大鼠 Monoclonal TX25 FITC
产品编号 ABIN1449203
发货至: 中国
  • 抗原 See all CD226 抗体
    CD226
    适用
    • 70
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    宿主
    • 54
    • 19
    • 3
    大鼠
    克隆类型
    • 49
    • 26
    • 1
    单克隆
    标记
    • 46
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD226 antibody is conjugated to FITC
    应用范围
    • 43
    • 30
    • 25
    • 13
    • 12
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody reacts with human CD226/DNAM-1.
    纯化方法
    Protein G agarose
    免疫原
    Recombinant human CD226/DNAM-1
    克隆位点
    TX25
    亚型
    IgG2a
    Top Product
    Discover our top product CD226 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS, 0.09 % NaN3, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    CD226
    别名
    CD226 / DNAM1 (CD226 产品)
    别名
    CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody
    背景
    CD226/DNAM-1 (DNAX accessory molecule-1) is a 65 kDa type I transmembrane glycoprotein expressed on the majority of T cells, NK cells, monocytes, and a subset of B-cells. A soluble form (50 kDa) of CD226 is present in normal serum and the supernatant of cultured activated T cells. Ligand binding to CD226 results in phosphorylation of Ser329 and Tyr322, suggesting a role in signal transduction. CD226 acts as an adhesion molecule involved in the binding of certain tumor cells to CTL and NK cells and mediates their cytotoxicity. CD226 also stimulates TNF-α and IFN-γ secretion by alloantigen-specific T cells.Synonyms: DNAM-1, DNAX accessory molecule 1
    基因ID
    10666
    NCBI登录号
    NP_006557
    UniProt
    Q15762
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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