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CYBA 抗体 (PE)

CYBA 适用: 人, 猴 FACS 宿主: 小鼠 Monoclonal 7D5 PE
产品编号 ABIN1449195
发货至: 中国
  • 抗原 See all CYBA 抗体
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    适用
    • 44
    • 19
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 猴
    宿主
    • 40
    • 4
    小鼠
    克隆类型
    • 40
    • 4
    单克隆
    标记
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYBA antibody is conjugated to PE
    应用范围
    • 35
    • 21
    • 17
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    This antibody recognizes the extracellular peptide portion of primate gp91phox of the Flavocytochrome b558.
    无交叉反应
    小鼠
    交叉反应 (详细)
    Species reactivity (tested):Human, Monkey.
    纯化方法
    Protein A agarose
    免疫原
    Human cytochrome b-rich fraction
    克隆位点
    7D5
    亚型
    IgG1
    Top Product
    Discover our top product CYBA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.09 % NaN3, 1 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原
    CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
    别名
    Cytochrome B-245 Light Chain (CYBA 产品)
    别名
    zgc:66077 antibody, MGC80750 antibody, CYBA antibody, p22-phox antibody, p22phox antibody, p22-PHOX antibody, b558 antibody, nmf333 antibody, P22-PHOX antibody, cytochrome b-245, alpha polypeptide antibody, cytochrome b-245 alpha polypeptide L homeolog antibody, cytochrome b-245 alpha polypeptide antibody, cytochrome b-245 light chain-like antibody, cytochrome b-245 alpha chain antibody, p22-phox antibody, cyba antibody, cyba.L antibody, CYBA antibody, LOC101328418 antibody, Cyba antibody
    背景
    The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome b558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
    基因ID
    1535
    NCBI登录号
    NP_000092
    UniProt
    P13498
    途径
    Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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