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- 抗原 See all CYBA 抗体
- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CYBA antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- This antibody reacts with an extracellular epitope of gp91phox. The antibody recognizes the epitope in the native conformation or after treatment with guanidine or urea, but SDS treatment will abolish antibody binding.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein-A agarose
- 免疫原
- Human cytochrome b rich fraction
- 克隆位点
- 7D5
- 亚型
- IgG1
- Top Product
- Discover our top product CYBA Primary Antibody
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anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 21-120) antibody
CYBA 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 128-195) antibodyCYBA 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 WB 宿主: 小鼠 Monoclonal 44-1 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) antibodyCYBA 适用: 人 WB, ELISA, IF, IHC (fro), FACS, ICC, IP 宿主: 小鼠 Monoclonal CS9 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (N-Term) antibodyCYBA 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 107-156) antibodyCYBA 适用: 人, 大鼠, 小鼠, 犬, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 117-145), (C-Term) antibodyCYBA 适用: 人 WB, IF 宿主: 兔 Polyclonal RB31767 unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (Middle Region) antibodyCYBA 适用: 人, 大鼠, 小鼠, Pig, 犬, 马, Cow, 兔, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-245, alpha Polypeptide (CYBA) (AA 124-153), (C-Term) antibodyCYBA 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2
- 储存液
- Azide free
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
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- 抗原
- CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))
- 别名
- Cytochrome B-245 Light Chain (CYBA 产品)
- 别名
- zgc:66077 antibody, MGC80750 antibody, CYBA antibody, p22-phox antibody, p22phox antibody, p22-PHOX antibody, b558 antibody, nmf333 antibody, P22-PHOX antibody, cytochrome b-245, alpha polypeptide antibody, cytochrome b-245 alpha polypeptide L homeolog antibody, cytochrome b-245 alpha polypeptide antibody, cytochrome b-245 light chain-like antibody, cytochrome b-245 alpha chain antibody, p22-phox antibody, cyba antibody, cyba.L antibody, CYBA antibody, LOC101328418 antibody, Cyba antibody
- 背景
- The NADPH oxidase is a multicomponent enzyme that transfers electrons from NADPH to O2 to generate superoxide (O2 -), a key part of the phagocytic or neutrophilic respiratory burst response. Flavocytochrome b558 is the catalytic component of the phagocyte NADPH oxidase. It is a transmembrane heterodimer composed of a large glycoprotein, gp91phox (PHagocyte OXidase) and a smaller protein, p22phox. Upon cell stimulation, flavocytochrome B558 assembles with p67phox, p47phox, and the GTP-binding protein Rac and becomes activated to generate O2 -. Mutations in gp91phox, p22phox, or other components of the NADPH oxidase can result in chronic granulomatous disease, which is associated with significant morbidity and mortality due to a predisposition to recurrent bacterial and fungal infections.Synonyms: CYBA, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox
- 基因ID
- 1535
- NCBI登录号
- NP_000092
- UniProt
- P13498
- 途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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