电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

STAT3 抗体 (pTyr705, pTyr708)

STAT3 适用: 人, 小鼠, 斑马鱼 WB 宿主: 小鼠 Monoclonal PS3-1 unconjugated
产品编号 ABIN1449165
发货至: 中国
  • 抗原 See all STAT3 抗体
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    抗原表位
    • 89
    • 54
    • 27
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 703-714, pTyr705, pTyr708
    适用
    • 276
    • 142
    • 135
    • 38
    • 25
    • 25
    • 22
    • 17
    • 17
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 斑马鱼
    宿主
    • 228
    • 57
    • 4
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 196
    • 95
    单克隆
    标记
    • 163
    • 23
    • 17
    • 10
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    This STAT3 antibody is un-conjugated
    应用范围
    • 217
    • 110
    • 75
    • 57
    • 51
    • 42
    • 41
    • 41
    • 27
    • 24
    • 15
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    CVTQPpYLKT KFI
    特异性
    This antibody reacts with human and mouse STAT3 phosphorylated at Tyr705, and zebrafish STAT3 phosphorylated at Tyr708.
    纯化方法
    Protein-A Sepharose
    免疫原
    12 amino acids peptide (a.a. 703~714) which contained the phosphorylated Tyr708 of zebrafish STAT3
    克隆位点
    PS3-1
    亚型
    IgG1
    Top Product
    Discover our top product STAT3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))
    别名
    STAT3 (STAT3 产品)
    别名
    1110034C02Rik antibody, AW109958 antibody, Aprf antibody, APRF antibody, HIES antibody, Xstat3 antibody, aprf antibody, hies antibody, stat3 antibody, wu:fc15d02 antibody, wu:fl59g06 antibody, z-Stat3 antibody, signal transducer and activator of transcription 3 antibody, signal transduction and activation of transcription 3 antibody, signal transducer and activator of transcription 3, gene 1 L homeolog antibody, signal transducer and activator of transcription 3 (acute-phase response factor) antibody, STAT3 antibody, stat3 antibody, Stat3 antibody, stat3.1.L antibody
    背景
    STAT (Signal Transducers and Activators of Transcription) proteins play important roles in development, cell differentiation, and cell cycle control. STAT3 is an ~85 kDa protein involved in the signaling pathways of many cytokines and growth factors, including GCSF and IL-6, where it functions as a negative regulator of transcription. STAT3 is also constitutively activated in a number of human tumors and it possesses anti-apoptotic activity and oncogenic potential. STAT3 may also regulate apoptosis by inhibiting NF?B. Activation of STAT3 by tyrosine phosphorylation results in dimerization, nuclear translocation, and DNA binding.Synonyms: APRF, Acute-phase response factor, STAT-3, Signal transducer and activator of transcription 3
    基因ID
    6774
    NCBI登录号
    NP_003141
    UniProt
    P40763
    途径
    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor
You are here:
客服