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CD8 alpha 抗体 (PE)

CD8A 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 53-6-7 PE
产品编号 ABIN135122
发货至: 中国
  • 抗原 See all CD8 alpha (CD8A) 抗体
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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    大鼠
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    This CD8 alpha antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD8α, Mr 32-34 kDa
    产品特性
    Rat Anti-Mouse CD8a-PE
    免疫原
    Spleen cells or thymocyte membranes
    克隆位点
    53-6-7
    亚型
    IgG2a
    Top Product
    Discover our top product CD8A Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 2 g/106 cells FITC and BIOT conjugates 2 g/106 cells AF488 conjugate 1 g/106 cells PE, APC, SPRD, PE/TXRD, CY5, PE/CY5.5, PE/CY7, 0.2 g/106 cells APC/CY5.5, APC/CY7, PACBLU, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vivo and in vitro depletion of CD8a+ cells

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    0.1 mg in 1.0 mL of PBS/Sodium azide and a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze!
    Protect conjugated products from light.

    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • Vaziry, Silim, Bleau, Frenette, Lamontagne: "Chicken infectious anaemia vaccinal strain persists in the spleen and thymus of young chicks and induces thymic lymphoid cell disorders." in: Avian pathology : journal of the W.V.P.A, Vol. 40, Issue 4, pp. 377-85, (2011) (PubMed).

  • 抗原
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    别名
    CD8a (CD8A 产品)
    别名
    cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
    背景
    In the mouse, CD8 exists in two forms: (i) a CD8 heterodimer composed of an chain (CD8/Lyt-2) and a chain (CD8/Lyt-3), and (ii) a homodimer of two chains. The heterodimer is found on the surface of essentially all thymocytes and the suppressor/cytotoxic subpopulation of mature T lymphocytes. Subsets of intestinal intraepithelial lymphocytes express CD8 without CD8. It has been suggested that CD8+- T cells mature extrathymically, while development of the CD8++ population of T cells is thymus-dependent. CD8 acts as a coreceptor with MHC Class I-restricted T cell receptors in antigen recognition and positive selection of MHC class I-restricted CD8+ T cells. In vivo and in vitro treatment with the 53-6.7 monoclonal antibody effectively depletes CD8+ cells.
    途径
    TCR Signaling
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