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BCL2L1 抗体 (AA 3-14)

BCL2L1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 2H12 unconjugated
产品编号 ABIN135025
发货至: 中国
  • 抗原 See all BCL2L1 抗体
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    抗原表位
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    AA 3-14
    适用
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    人, 小鼠
    宿主
    • 157
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BCL2L1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB)
    特异性
    Mouse/Rat/Human Bcl-xL
    产品特性
    Mouse Anti-Bcl-xL-UNLB
    纯化方法
    Purified
    免疫原
    Bcl-xL peptide (a.a. 3-14) common to mouse and human
    克隆位点
    2H12
    亚型
    IgG2a
    Top Product
    Discover our top product BCL2L1 Primary Antibody
  • 应用备注
    • Applications: WB - Quality tested , IP - Reported in literature , FC - Reported in literature , IHC-PS - Reported in literature , ELISA - Reported in literature
    • Working Dilutions: Immunoblotting Purified (UNLB) antibody ≤ 2 g/mL
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    别名
    Bcl-xL (BCL2L1 产品)
    别名
    BCL-XL/S antibody, BCL2L antibody, BCLX antibody, BCLXL antibody, BCLXS antibody, Bcl-X antibody, PPP1R52 antibody, bcl-xL antibody, bcl-xS antibody, Bcl(X)L antibody, Bcl-XL antibody, Bcl-Xs antibody, Bcl2l antibody, BclX antibody, bcl-x antibody, Bcl-xl antibody, Bclx antibody, bcl-X antibody, Bcl-xL antibody, BCL-XL antibody, BCL2L1 antibody, bcl-XL antibody, bcl-x(l) antibody, bcl-xl/s antibody, bcl-xs antibody, bcl2l antibody, bclx antibody, bclxl antibody, xR11 antibody, bcl-xl antibody, blp1 antibody, cb1021 antibody, zfBLP1 antibody, BCL2 like 1 antibody, BCL2-like 1 antibody, Bcl2-like 1 antibody, BCL2-like 1 L homeolog antibody, bcl2-like 1 antibody, BCL2L1 antibody, Bcl2l1 antibody, bcl2l1 antibody, bcl2l1.L antibody
    背景
    Apoptosis, or programmed cell death, is a well-documented phenomenon in many cellular systems. It plays a key role in tissue and organ development as well as in adult tissues during cell turnover. Apoptosis can be induced by a variety of internal and external stimuli including growth factor deprivation, cytokine treatment, antigen-receptor engagement, cell-cell interactions, irradiation and glucocorticoid treatment. Bcl-2 and one of its homologues, Bcl-xL, protect cells from apoptosis, while other homologues of Bcl-2 such as Bax, Bad and Bak have been shown to enhance apoptosis. Bcl-xL has been shown to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. In contrast, Bad and Bax inhibit the protective functions of Bcl-xL and Bcl-2, respectively. Although heterodimerization between Bcl-xL/Bad and Bcl-2/Bax was originally thought to be essential for the differential anti-apoptotic activity of Bcl-xL and Bcl-2, other results suggest that the formation of heterodimers may not be necessary for this death-repressing activity.
    途径
    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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