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- 抗原 See all LRP5 抗体
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRP5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应 (详细)
- Species reactivity (tested):Human and Mouse.
- 纯化方法
- Affinity Chromatography
- 免疫原
- Synthetic peptide surrounding amino acid 437 of Human LRP.
- 亚型
- IgG
- Top Product
- Discover our top product LRP5 Primary Antibody
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- 应用备注
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Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal as preservative
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Store the antibody undiluted at -20 °C or at -70 °C (in aliquots) for long term storage.
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Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146710, (2016) (PubMed).
: "Hypoxia-mediated impairment of the mitochondrial respiratory chain inhibits the bactericidal activity of macrophages." in: Infection and immunity, Vol. 80, Issue 4, pp. 1455-66, (2012) (PubMed).
: "Coordinated action of CK1 isoforms in canonical Wnt signaling." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2877-88, (2011) (PubMed).
: "A p120-catenin-CK1epsilon complex regulates Wnt signaling." in: Journal of cell science, Vol. 123, Issue Pt 15, pp. 2621-31, (2010) (PubMed).
: "Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration." in: American journal of physiology. Cell physiology, Vol. 298, Issue 3, pp. C550-8, (2010) (PubMed).
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Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146710, (2016) (PubMed).
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- 抗原
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
- 别名
- LRP5 + LRP6 (LRP5 产品)
- 背景
- LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Want signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental processes in Xenopus embryos. Mice lacking LRP-6 exhibited developmental defects that are similar to those caused by deficiencies in various Want proteins. Recent work also shows that Want proteins induce the binding of LRP-5 to Axin, leading Axin degradation and beta-catenin stabilization.Synonyms: LRP5, LRP6, LRP7, Low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 6
- 途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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