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LRP5 抗体

LRP5 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127323
发货至: 中国
  • 抗原 See all LRP5 抗体
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    适用
    • 59
    • 46
    • 22
    • 1
    • 1
    人, 小鼠
    宿主
    • 68
    • 5
    • 1
    • 1
    克隆类型
    • 71
    • 4
    多克隆
    标记
    • 27
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    This LRP5 antibody is un-conjugated
    应用范围
    • 44
    • 38
    • 26
    • 20
    • 13
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB)
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Affinity Chromatography
    免疫原
    Synthetic peptide surrounding amino acid 437 of Human LRP.
    亚型
    IgG
    Top Product
    Discover our top product LRP5 Primary Antibody
  • 应用备注
    Western Blot: 0.5-4.0 μg/mL. Jurkat cell lysate can be used as a Positive Control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal as preservative
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or at -70 °C (in aliquots) for long term storage.
  • Moon, Lee, Kim, Cho, Lee, Kim, Park, Cho, Lee, Oh: "Inhibition of Hepatitis C Virus in Mice by a Small Interfering RNA Targeting a Highly Conserved Sequence in Viral IRES Pseudoknot." in: PLoS ONE, Vol. 11, Issue 1, pp. e0146710, (2016) (PubMed).

    Wiese, Gerlach, Popp, Matuszak, Mahapatro, Castiglione, Chakravortty, Willam, Hensel, Bogdan, Jantsch: "Hypoxia-mediated impairment of the mitochondrial respiratory chain inhibits the bactericidal activity of macrophages." in: Infection and immunity, Vol. 80, Issue 4, pp. 1455-66, (2012) (PubMed).

    Del Valle-Pérez, Arqués, Vinyoles, de Herreros, Duñach: "Coordinated action of CK1 isoforms in canonical Wnt signaling." in: Molecular and cellular biology, Vol. 31, Issue 14, pp. 2877-88, (2011) (PubMed).

    Casagolda, Del Valle-Pérez, Valls, Lugilde, Vinyoles, Casado-Vela, Solanas, Batlle, Reynolds, Casal, de Herreros, Duñach: "A p120-catenin-CK1epsilon complex regulates Wnt signaling." in: Journal of cell science, Vol. 123, Issue Pt 15, pp. 2621-31, (2010) (PubMed).

    Danieli-Betto, Peron, Germinario, Zanin, Sorci, Franzoso, Sandonà, Betto: "Sphingosine 1-phosphate signaling is involved in skeletal muscle regeneration." in: American journal of physiology. Cell physiology, Vol. 298, Issue 3, pp. C550-8, (2010) (PubMed).

  • 抗原
    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
    别名
    LRP5 + LRP6 (LRP5 产品)
    背景
    LDL-related proteins LRP-5 and LRP-6. are members of the LDL receptor superfamily, which were found to be involved in the canonical Want signaling pathway. Mammalian LRP-6 was shown to bind to Wnt-1 and enhance Induced-induced developmental processes in Xenopus embryos. Mice lacking LRP-6 exhibited developmental defects that are similar to those caused by deficiencies in various Want proteins. Recent work also shows that Want proteins induce the binding of LRP-5 to Axin, leading Axin degradation and beta-catenin stabilization.Synonyms: LRP5, LRP6, LRP7, Low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 6
    途径
    WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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