RNF216 抗体 (N-Term)
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- 抗原 See all RNF216 抗体
- RNF216 (Ring Finger Protein 216 (RNF216))
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抗原表位
- N-Term
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF216 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Ion exchange chromatography
- Top Product
- Discover our top product RNF216 Primary Antibody
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anti-Ring Finger Protein 216 (RNF216) (C-Term) antibody
RNF216 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 216 (RNF216) (N-Term) antibodyRNF216 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 216 (RNF216) (C-Term) antibodyRNF216 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline, 0.02 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- 抗原
- RNF216 (Ring Finger Protein 216 (RNF216))
- 别名
- RNF216 (RNF216 产品)
- 别名
- RGD1565135 antibody, TRIAD3 antibody, RNF216 antibody, zin antibody, u7i1 antibody, triad3 antibody, ubce7ip1 antibody, MGC147026 antibody, 2810055g22rik antibody, 2810055G22Rik antibody, AI647468 antibody, AU019462 antibody, C86502 antibody, F830018F18Rik antibody, UIP83 antibody, Ubce7ip1 antibody, CAHH antibody, U7I1 antibody, UBCE7IP1 antibody, ZIN antibody, ring finger protein 216 antibody, Rnf216 antibody, RNF216 antibody, rnf216 antibody
- 背景
- TRIAD3A is a ubiquitously expressed E3 ubiquitin-protein ligase which plays an important role in the innate immune response. Regulation of the level and duration of Toll-like receptor (TLR) activation is vital in controlling a pro-inflammatory response, to prevent harm to the host. Several proteins involved in the regulation of TLR signaling have been described including ST2 and IL-1R-associated kinase M, along with many other adaptor proteins of the MyD88 family, which mediate TLR signal transduction. TRIAD3A, identified as a RING finger member of the E3 ligase family of proteins, binds to the cytoplasmic tail of several TLRs, notably TLR4 and TLR9, resulting in ubiquitination and proteolytic degradation, thereby regulating their expression. TRIAD3A does not appear to regulate the expression of TLR2.Synonyms: E3 ubiquitin-protein ligase RNF216, RING finger protein 216, TRIAD3, Triad domain-containing protein 3, UBCE7IP1, Ubiquitin-conjugating enzyme 7-interacting protein 1, ZIN, Zinc finger protein inhibiting NF-kappa-B
- UniProt
- Q9NWF9
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