MIF 抗体 (Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)) (AA 1-114)

Details for Product anti-MIF Antibody No. ABIN121160, 供应商: Log in to see
抗原
  • mif
  • Mif
  • gif
  • glif
  • mmif
  • LOC100136498
  • LOC100284350
  • LOC100284546
  • GIF
  • Glif
  • GLIF
  • MMIF
  • macrophage migration inhibitory factor (glycosylation-inhibiting factor)
  • macrophage migration inhibitory factor
  • Macrophage migration inhibitory factor
  • mif
  • MIF
  • Mif
  • PHATRDRAFT_49660
  • LOC100136498
  • LOC100284350
  • LOC100284546
  • LOC100338701
抗原表位
AA 1-114, N-Term
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适用

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宿主
小鼠
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克隆类型 (克隆位点)
单克隆 ()
标记
This MIF antibody is un-conjugated
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应用范围
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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选项
Supplier
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Supplier Product No.
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免疫原 Recombinant human MIF (1-114 aa) purified from E. coli
克隆位点 4-00E-004
亚型 IgG1
特异性 The antibody recognizes Human MIF. Other species not tested.
纯化方法 Protein-G affinity chromatography
别名 MIF (MIF Antibody 摘要)
背景 The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T-cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.Synonyms: GLIF, Glycosylation-inhibiting factor, MMIF, Macrophage migration inhibitory factor, Phenylpyruvate tautomerase
基因ID 4282
UniProt P14174
研究领域 Immunology, Innate Immunity, Cytokines, Inflammation
途径 Regulation of Systemic Arterial Blood Pressure by Hormones, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
应用备注 ELISA. Western blot (1/500 - 1/2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
状态 Liquid
浓度 1.0 mg/mL
缓冲液 PBS, pH 7.4, containing 0.09 % sodium azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
有效期 12 months
厂商提供的图像
Western Blotting (WB) image for anti-Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor) (MIF) (AA 1-114), (N-Term) antibody (ABIN121160) Western blot analysis.,.The extract of HL-60 was resolved by SDS-PAGE, transferred to...
背景 Richard, Amador Del Valle, Moreau, Milpied, Felice, Daeschler, Harousseau, Richet: "Viridans streptococcal bacteraemia in patients with neutropenia." in: Lancet, Vol. 345, Issue 8965, pp. 1607-9, 1995 (PubMed).

Bernhagen, Mitchell, Calandra, Voelter, Cerami, Bucala: "Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF)." in: Biochemistry, Vol. 33, Issue 47, pp. 14144-55, 1994 (PubMed).

Weiser, Temple, Witek-Giannotti, Remold, Clark, David: "Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 19, pp. 7522-6, 1989 (PubMed).

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