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CD161 抗体

KLRB1 适用: 大鼠 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 01-10-78 unconjugated
产品编号 ABIN120522
发货至: 中国
  • 抗原 See all CD161 (KLRB1) 抗体
    CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
    适用
    • 48
    • 15
    • 6
    • 3
    • 2
    • 2
    大鼠
    宿主
    • 44
    • 17
    小鼠
    克隆类型
    • 43
    • 18
    单克隆
    标记
    • 26
    • 10
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD161 antibody is un-conjugated
    应用范围
    • 41
    • 24
    • 12
    • 10
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    纯化方法
    Protein G affinity chromatography.
    免疫原
    Purified splenic NK cells from the LEW rat strain.
    克隆位点
    01-10-78
    亚型
    IgG1
    Top Product
    Discover our top product KLRB1 Primary Antibody
  • 应用备注
    Flow Cytometry: 1/50-1/100, use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Imunoprecipitation. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4 with 0.09 % sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycle.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2-8 °C or -20 °C. After reconstitution, aliquot and freeze unused portions in volumes appropriate for single usage.
  • 抗原
    CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
    别名
    CD161 / KLRB1 (KLRB1 产品)
    背景
    Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 (CD161) protein contains an extracellular domain with several motifs characteristic of C type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. In mouse the NKRP1 family has three members, NKRP1A, B and C, whilst in human only one member has been identified. The human protein has received the designation CD161, and the mouse proteins have been referred to as CD161a, b and c. Engagement of CD161c has been reported to have activating function in NK cells, whilst engagement of CD161b is inhibitory.Synonyms: C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, NKRP1A, Natural killer cell surface protein P1A
    基因ID
    3820
    NCBI登录号
    NP_002249
    UniProt
    Q12918
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