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KLRK1 抗体 (PE)

KLRK1 适用: 人 FACS 宿主: 小鼠 Monoclonal 1D11 PE
产品编号 ABIN120295
发货至: 中国
  • 抗原 See all KLRK1 抗体
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This KLRK1 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody is specific for CD314 also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6). We recommend the use of SM2260LE for such studies.
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    NKL cells. Spleen cells from immunised RBF/DnJ mice were fused with cells of the p3 mouse myeloma cell line.
    克隆位点
    1D11
    亚型
    IgG1
    Top Product
    Discover our top product KLRK1 Primary Antibody
  • 应用备注
    Flow Cytometry (Neat-1/10): Use 10 μL of the suggested working dilution to label 106 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1.0 mL distilled water
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • 抗原
    KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))
    别名
    CD314 / KLRK1 (KLRK1 产品)
    别名
    KLRK1 antibody, NKG2D antibody, CD314 antibody, D12S2489E antibody, KLR antibody, NKG2-D antibody, D6H12S2489E antibody, Nkg2d antibody, Nkrp2 antibody, killer cell lectin like receptor K1 antibody, killer cell lectin-like receptor subfamily K, member 1 antibody, NKG2D protein antibody, KLRK1 antibody, Klrk1 antibody, NKG2D antibody
    背景
    CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells.Synonyms: D12S2489E, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2D
    基因ID
    100528032
    NCBI登录号
    NP_001186734
    UniProt
    P26718
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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