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CD163 抗体

CD163 适用: 人, 猴, 绵羊 WB, FACS, IHC (p), IF, IHC (fro), EIA 宿主: 小鼠 Monoclonal EDHu-1 unconjugated
产品编号 ABIN120083
发货至: 中国
  • 抗原 See all CD163 抗体
    CD163
    适用
    • 131
    • 50
    • 30
    • 29
    • 20
    • 4
    • 4
    人, 猴, 绵羊
    宿主
    • 112
    • 43
    • 1
    小鼠
    克隆类型
    • 96
    • 59
    • 1
    单克隆
    标记
    • 55
    • 18
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    • 7
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    • 3
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    • 1
    • 1
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    This CD163 antibody is un-conjugated
    应用范围
    • 113
    • 70
    • 54
    • 41
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    • 19
    • 15
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognises the CD163 cell surface antigen. Clone EDHu-1 is reported to inhibit the binding of haptoglobin:haemoglobin to CD163.
    交叉反应 (详细)
    Species reactivity (tested):Human, Rhesus Monkey, Sheep.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Leucocytes harvested from pleural cavity of patients with idiopathic spontaneous pneumothorax.
    克隆位点
    EDHu-1
    亚型
    IgG1
    Top Product
    Discover our top product CD163 Primary Antibody
  • 应用备注
    Flow Cytometry. Immunohistochemistry on frozen sections. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.4, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD163
    别名
    CD163 (CD163 产品)
    别名
    DMBT1 antibody, CD163 antibody, CD163v2 antibody, CD163v3 antibody, M130 antibody, MM130 antibody, deleted in malignant brain tumors 1 protein-like antibody, CD163 molecule antibody, CD163 antigen antibody, LOC426820 antibody, CD163 antibody, Cd163 antibody
    背景
    CD163 is a 130-140kD glycoprotein expressed by tissue macrophages. CD163 is not expressed by resting peripheral blood leucocytes, but expression may be induced on monocytes by culture in dexamethasone. It is a member of the scavenger receptor cysteine-rich superfamily and is a receptor for the hemoglobin-haptoglobin complex. CD163 is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation. CD163 is present on all CD14 positive monocytes, most CD64 positive monocytes, and shows higher expression on CD16 positive monocytes. CD163 is upregulated on mononuclear phagocytes by IL-10, IL-6 and dexamethasone. Lipopolysaccharide (LPS) and phorbol myristate acetate (PMA) both induce shedding of CD163 from the cell surface into plasma or cell supernatant.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130
    基因ID
    9332
    NCBI登录号
    NP_004235
    UniProt
    Q86VB7
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