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CD79a 抗体 (FITC)

CD79A 适用: 人 FACS 宿主: 小鼠 Monoclonal ZL7-4 FITC
产品编号 ABIN118795
发货至: 中国
  • 抗原 See all CD79a (CD79A) 抗体
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD79a antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with CD79a positive cells by flow cytometry. This clone has been reported to be useful in distinguishing B-CLL from mantle cell lymphoma in flow cytometric assays.
    免疫原
    IgM complex isolated from Daudi cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
    克隆位点
    ZL7-4
    亚型
    IgG1
    Top Product
    Discover our top product CD79A Primary Antibody
  • 应用备注
    Flow Cytometry: Use 10 μL of neat antibody to label 1x10^6 cells in 100 μL. We recommend incubation times of at least 30 minutes with this antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
    别名
    CD79a (CD79A 产品)
    别名
    CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody
    背景
    A disulfide-linked heterodimer, consisting of CD79a / mb1 and CD79b / B29 polypeptides, is non-covalently associated with membrane bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. The CD79a/b heterodimer interacts with at least one tyrosine kinase (Lyn). Induction of tyrosine kinase activity after antigen binding causes phosphorylation of the CD79a/b dimer, and also of other molecules, thereby initiating intracellular signaling.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
    基因ID
    973
    NCBI登录号
    NP_001774
    UniProt
    P11912
    途径
    BCR Signaling
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