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Integrin alpha 1 抗体 (FITC)

ITGA1 适用: 人 FACS 宿主: 小鼠 Monoclonal TS2-7 FITC
产品编号 ABIN118691
发货至: 中国
  • 抗原 See all Integrin alpha 1 (ITGA1) 抗体
    Integrin alpha 1 (ITGA1)
    适用
    • 66
    • 33
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    • 1
    宿主
    • 53
    • 15
    • 1
    • 1
    小鼠
    克隆类型
    • 58
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    单克隆
    标记
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    • 2
    • 2
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    This Integrin alpha 1 antibody is conjugated to FITC
    应用范围
    • 49
    • 23
    • 22
    • 14
    • 13
    • 13
    • 12
    • 7
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    • 5
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    Flow Cytometry (FACS)
    纯化方法
    Affinity Chromatography on Protein G.
    克隆位点
    TS2-7
    亚型
    IgG1
    Top Product
    Discover our top product ITGA1 Primary Antibody
  • 应用备注
    Flow cytometry: Neat-1/5, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Integrin alpha 1 (ITGA1)
    别名
    CD49a / ITGA1 (ITGA1 产品)
    别名
    CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody
    背景
    Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around twenty two different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. Alpha 1 integrin along with alpha 2, alpha L and alpha M has a unique inserted domain. Integrin alpha 1 is a receptor for laminin and collagen. The alpha1 subunit is also known as CD49a. CD49a associates with CD29 (beta 1 integrin), to form an alpha1 beta1 heterodimer, identified as the rat homologue to VLA1, which is involved in cellular adhesion to laminin and collagen.Synonyms: CD49 antigen-like family member A, ITGA-1, Integrin alpha-1, Laminin and Collagen Receptor, VLA-1, VLA1
    基因ID
    3672
    NCBI登录号
    NP_852478
    UniProt
    P56199
    途径
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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