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CD4 抗体 (FITC)

CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal RPA-T4 FITC
产品编号 ABIN118485
发货至: 中国
  • 抗原 See all CD4 抗体
    CD4
    适用
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    小鼠
    克隆类型
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    标记
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    This CD4 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises CD4. Epitope mapping studies have shown that antibodies, produced by clone RPA-T4, recognise an epitope within domain 1, of the extracellular region, of the CD4 Molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation. We recommend the use of SM1058LE for this purpose.
    纯化方法
    Affinity chromatography on Protein G.
    免疫原
    Human PHA blasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NSI myeloma cell line.
    克隆位点
    RPA-T4
    亚型
    IgG1
    Top Product
    Discover our top product CD4 Primary Antibody
  • 应用备注
    Flow Cytometry: Use 10 μL of neat antibody to label 10^6 cells or 100 μL of lysed whole peripheral blood.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD4
    别名
    CD4 (CD4 产品)
    别名
    cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
    背景
    CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
    基因ID
    920
    NCBI登录号
    NP_000607
    UniProt
    P01730
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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