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CD3 抗体 (APC)

CD3 适用: 人, 灵长类 FACS 宿主: 小鼠 Monoclonal UCHT1 APC
产品编号 ABIN118476
发货至: 中国
  • 抗原 See all CD3 抗体
    CD3
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    人, 灵长类
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD3 antibody is conjugated to APC
    应用范围
    • 266
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises a surface protein of peripheral blood T cells of molecular weight 19 kDa. As a pan T cell marker this antibody is present on more than 95 % of circulating human peripheral T cells.
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome. Spleen cells from immunised BALB/c mice were fused with cells of the P3/NS1/1-Ag4-1 mouse myeloma cell line.
    克隆位点
    UCHT1
    亚型
    IgG1
    Top Product
    Discover our top product CD3 Primary Antibody
  • 应用备注
    Flow Cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with distilled water
    缓冲液
    PBS, pH 7.2, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    别名
    CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
    背景
    T Cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    基因ID
    916
    NCBI登录号
    NP_000724
    UniProt
    P07766
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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