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Cullin 5 抗体 (N-Term)

CUL5 适用: 人, 小鼠 WB, IHC (p), IP, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN117951
发货至: 中国
  • 抗原 See all Cullin 5 (CUL5) 抗体
    Cullin 5 (CUL5)
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 4-18, N-Term
    适用
    • 45
    • 20
    • 17
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 44
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cullin 5 antibody is un-conjugated
    应用范围
    • 20
    • 13
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    序列
    Human Cullin 5 (780 aa 90.9 kDa): 1 matsnllknk gslqfedkwd fmrpivlkll rqesvtkqqw fdlfsdvhav clwddkgpak 61 ihqalkedil efikqaqarv lshqddtall kayivewrkf ftqcdilpkp fcqleitlmg 121 kqgsnkksnv edsivrklml dtwnesifsn iknrlqdsam klvhaerlge afdsqlvigv 181 resyvnlcsn pedklqiyrd nfekayldst erfyrtqaps ylqqngvqny mkyadaklke 241 eekralryle trrecnsvea lmeccvnalv tsfketilae cqgmikrnet eklhlmfslm 301 dkvpngiepm lkdleehiis agladmvaaa etittdseky veqlltlfnr fsklvkeafq 361 ddprfltard kaykavvnda tifklelplk qkgvglktqp eskcpellan ycdmllrktp 421 lskkltseei eaklkevllv lkyvqnkdvf mryhkahltr rlildisads eieenmvewl 481 revgmpadyv nklarmfqdi kvsedlnqaf kemhknnkla lpadsvniki lnagawsrss 541 ekvfvslpte ledlipevee fykknhsgrk lhwhhlmsng iitfknevgq ydlevttfql 601 avlfawnqrp rekisfenlk latelpdael rrtlwslvaf pklkrqvlly epqvnspkdf 661 tegtlfsvnq efsliknakv qkrgkinlig rlqlttermr eeenegivql rilrtqeaii 721 qimkmrkkis naqlqtelve ilknmflpqk kmikeqiewl iehkyirrde sdintfiyma
    特异性
    This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human Cullin 5. Cross reactivity is expected against mouse Cul5 based on a high degree of sequence homology. Cross reactivity with other human cullins may occur.
    纯化方法
    Delipidation and defibrination.
    免疫原
    Synthetic peptide corresponding to amino acids 4-18 of Human Cul5 (N-terminus) coupled coupled to KLH.
    Top Product
    Discover our top product CUL5 Primary Antibody
  • 应用备注
    Western blot (1/500-1/1,000): This antibody reacts with human Cul5. An 90.9 kDa bandcorresponding to human Cul5 is detected, Most cell lines expressing Cul5 can be used as a
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    85.0 mg/mL (by Refractometry)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for up to one month or in aliquots at -20 °C for longer.
  • Ng, Yu, Lai, Lau: "Biliary Complications Associated with Selective Internal Radiation (SIR) Therapy for Unresectable Liver Malignancies." in: Digestive diseases and sciences, (2008) (PubMed).

  • 抗原
    Cullin 5 (CUL5)
    别名
    Cullin-5 (CUL5 产品)
    别名
    cul5 antibody, wu:fd17d09 antibody, wu:fi20h12 antibody, xx:11fd17d09 antibody, zgc:66185 antibody, Xcullin5 antibody, CG1401 antibody, CUL5 antibody, Cul5 antibody, Cullin 5 antibody, Cullin5 antibody, Dmel\\CG1401 antibody, cul-5 antibody, vacm-1 antibody, vacm1 antibody, VACM-1 antibody, VACM1 antibody, 4921514I20Rik antibody, 8430423K24Rik antibody, AI852817 antibody, C030032G03Rik antibody, C330021I08Rik antibody, Cullin-5 antibody, cullin 5a antibody, cullin 5 L homeolog antibody, Cullin 5 antibody, cullin 5 antibody, Cullin-5 antibody, cul5a antibody, cul5.L antibody, Cul5 antibody, CUL5 antibody, cul5 antibody, cul-5 antibody
    背景
    Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 5 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 5 seems to be involved proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. Cullin 5 may form a cell surface vasopressin receptor. Cullin 5 is part of a E3 ubiquitin ligase complex with elongin BC complex (TCEB1 and TCEB2), RBX1 and MUF1, complexes with elongin BC complex (TCEB1 and TCEB2), RXB1 and TCEB3 or SOCS1 or WSB1, elongin BC complex (TCEB1 and TCEB2), RBX1 and VHL, elongin BC complex (TCEB1 and TCEB2), RBX1, adenovirus type 5 E1B-55 kDa protein and adenovirus type 5 E4-orf6. Cullin 5 Interacts with RBX1 and RNF7.Synonyms: CUL-5, CUL5, VACM-1, VACM1, Vasopressin-activated calcium-mobilizing receptor
    基因ID
    8065
    NCBI登录号
    NP_003469
    UniProt
    Q93034
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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