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Cullin 3 抗体 (N-Term)

Name: Cullin 3 抗体 (N-Term)
SKU: ABIN117949
Availability: OutOfStock

CUL3 适用: 人, 小鼠 WB, IHC (p), IP, EIA 宿主: 兔 Polyclonal unconjugated

Conjugation pathways for ubiquitin and ubiquitin-like modifiers (UBLs).

1 image

(1 reference)

产品编号 ABIN117949

发货至: 中国

Datasheet as PDF

抗原 See all Cullin 3 (CUL3) 抗体

Cullin 3 (CUL3)
抗原表位
15

5

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 1-12, N-Term
适用
52

22

18

6

5

5

4

3

3

3

3

2

2

2

1
人, 小鼠
宿主
50

1

1
兔
Compatible Secondaries
克隆类型
48

4
多克隆
标记
31

2

2

2

2

2

2

2

1

1

1

1

1

1

1
This Cullin 3 antibody is un-conjugated
应用范围
24

15

13

13

13

6

6

5

3

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

序列

Human Cullin 3 (768 aa 88.9 kDa): 1 msnlskgtgs rkdtkmrira fpmtmdekyv nsiwdllkna iqeiqrknns glsfeelyrn 61 aytmvlhkhg eklytglrev vtehlinkvr edvlnslnnn flqtlnqawn dhqtamvmir 121 dilmymdrvy vqqnnvenvy nlgliifrdq vvrygcirdh lrqtlldmia rerkgevvdr 181 gairnacqml milglegrsv yeedfeapfl emsaeffqme sqkflaensa svyikkvear 241 ineeiervmh cldksteepi vkvverelis khmktiveme nsglvhmlkn gktedlgcmy 301 klfsrvpngl ktmcecmssy lreqgkalvs eegegknpvd yiqglldlks rfdrfllesf 361 nndrlfkqti agdfeyflnl nsrspeylsl fiddklkkgv kglteqevet ildkamvlfr 421 fmqekdvfer yykqhlarrl ltnksvsdds eknmisklkt ecgcqftskl egmfrdmsis 481 nttmdefrqh lqatgvslgg vdltvrvltt gywptqsatp kcnippaprh afeifrrfyl 541 akhsgrqltl qhhmgsadln atfygpvkke dgsevgvgga qvtgsntrkh ilqvstfqmt 601 ilmlfnnrek ytfeeiqqet diperelvra lqslacgkpt qrvltkepks keienghift 661 vndqftsklh rvkiqtvaak qgesdperke trqkvdddrk heieaaivri mksrkkmqhn 721 vlvaevtqql karflpspvv ikkrieglie reylartped rkvytyva

特异性

This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human Cullin 3. Cross reactivity is expected against mouse Cul3 based on sequence homology. Cross reactivity with other human cullins is unlikely based on sequence homology.

纯化方法

Delipidation and defibrination.

免疫原

Synthetic peptide corresponding to amino acids 1-12 of Human Cul3 (N-terminus) coupled to KLH.

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anti-Cullin 3 (CUL3) (AA 411-510) antibody
CUL3 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) antibody
CUL3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (AA 569-768) antibody
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anti-Cullin 3 (CUL3) (AA 301-400) antibody
CUL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A3 unconjugated

anti-Cullin 3 (CUL3) (AA 618-667) antibody
CUL3 适用: 人, 斑马鱼, Cow, 小鸡, 犬, 豚鼠, 马, 兔, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (N-Term) antibody
CUL3 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (N-Term) antibody
CUL3 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Cullin 3 (CUL3) (Internal Region) antibody
Verified CUL3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

应用备注

Western blot: This antibody reacts with human Cul3 (1/500-1/1,000, An 88.9 kDa bandcorresponding to human Cul3 is detected, Most cell lines expressing Cul3 can be used as apositive control).

限制

仅限研究用
状态

Liquid

浓度

85.0 mg/mL (by Refractometry)

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store undiluted at 2-8 °C for up to one month or at -20 °C for longer.
Chuang, Huang, Hsieh, Jung, Ye, Du, Lu, Cho, Hsiao, Hsu, Lin: "Sporadic paediatric and adult Burkitt lymphomas share similar phenotypic and genotypic features." in: Histopathology, Vol. 52, Issue 4, pp. 427-35, (2008) (PubMed).
抗原

Cullin 3 (CUL3)

别名

Cullin-3 (CUL3 产品)

别名

CUL-3 antibody, Cullin-3 antibody, CUL-3-A antibody, Cullin-3-A antibody, cul3 antibody, cul3a antibody, CUL-3-B antibody, Cullin-3-B antibody, cul3b antibody, wu:fc37e01 antibody, CUL3 antibody, ATCUL3 antibody, ATCUL3A antibody, CUL3A antibody, T24P13.25 antibody, cullin 3 antibody, cullin 3A antibody, PHA2E antibody, AI467304 antibody, AW146203 antibody, mKIAA0617 antibody, cullin 3 antibody, cullin 3 L homeolog antibody, cullin 3 S homeolog antibody, cullin-3 antibody, Cullin-3 (CUL-3) antibody, cullin 3a antibody, CULlin antibody, CUL3 antibody, cul3 antibody, cul3.L antibody, cul3.S antibody, PTRG_11586 antibody, Smp_117580 antibody, cul3a antibody, Cul3 antibody, cul-3 antibody

背景

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 3 is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cul3 serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cul3 may also contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Unlike Cul1 and Cul2, Cul3 seems not to be a part of the SCF complex consisting of CUL1, RBX1, SKP1 and SKP2. Cul3 also interacts with RNF7 and is part of a complex with TIP120A/CAND1, Cyclin E and RBX1.Synonyms: CUL-3, CUL3, KIAA0617

基因ID

8452

NCBI登录号

NP_003581

UniProt

Q13618

途径

M Phase