CAND1 抗体 (N-Term)
(2 references)-
- 抗原 See all CAND1 抗体
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
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抗原表位
- AA 11-24, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAND1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- 序列
- Human CAND1 (TIP120A) (1230 aa 136.4 kDa): 1 masasyhisn llekmtssdk dfrfmatndl mtelqkdsik ldddserkvv kmilklledk 61 ngevqnlavk clgplvskvk eyqvetivdt lctnmlsdke qlrdissigl ktvigelppa 121 ssgsalaanv ckkitgrlts aiakqedvsv qlealdimad mlsrqggllv nfhpsiltcl 181 lpqltsprla vrkrtiialg hlvmscgniv fvdliehlls elskndsmst trtyiqciaa 241 isrqaghrig eylekiiplv vkfcnvddde lreyciqafe sfvrrcpkev yphvstiini -- 901 sqpkrqylll hslkeiissa svvglkpyve niwalllkhc ecaeegtrnv vaeclgkltl 961 idpetllprl kgylisgssy arssvvtavk ftisdhpqpi dpllkncigd flktledpdl 1021 nvrrvalvtf nsaahnkpsl irdlldtvlp hlynetkvrk elirevemgp fkhtvddgld 1081 irkaafecmy tlldscldrl difeflnhve dglkdhydik mltflmlvrl stlcpsavlq 1141 rldrlveplr atcttkvkan svkqefekqd elkrsamrav aalltipeae ksplmsefqs 1201 qissnpelaa ifesiqkdss stnlesmdts
- 特异性
- This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This antibody reacts with human, rat and mouse CAND1/TIP120A. Cross reactivity does occur with human, rat and mouse CAND2/TIP120B. Cross reactivity with CAND1 from other sources is not known.
- 纯化方法
- Delipidation and defibrination.
- 免疫原
- This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 11-24 of Human CAND1/TIP120A (N- terminal) coupled to KLH.
- Top Product
- Discover our top product CAND1 Primary Antibody
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anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibody
CAND1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5D7 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1-100) antibodyCAND1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F2 unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 750-980) antibodyCAND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1150-1230) antibodyCAND1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) antibodyCAND1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (C-Term) antibodyCAND1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, Hamster, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 112-161) antibodyCAND1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, Hamster, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cullin-Associated and Neddylation-Dissociated 1 (CAND1) (AA 1180-1230) antibodyCAND1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 小鸡 WB, IHC, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Western blot (1: 500-1: 1,000). Immunoprecipitation: The antibody immunoprecipitates in vitro translated protein andprotein from cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 85 mg/mL (by Refractometry)
- 注意事项
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." in: Transplantation, Vol. 85, Issue 3, pp. 398-406, (2008) (PubMed).
: "High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected nonsmall cell lung cancer." in: British journal of cancer, (2008) (PubMed).
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: "Living donor liver transplantation for hepatocellular carcinoma: a single-center experience in Taiwan." in: Transplantation, Vol. 85, Issue 3, pp. 398-406, (2008) (PubMed).
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- 抗原
- CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))
- 别名
- CAND1 (CAND1 产品)
- 背景
- CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.Synonyms: Cullin-associated NEDD8-dissociated protein 1, Cullin-associated and neddylation-dissociated protein 1, KIAA0829, TBP-interacting protein TIP120A, TBP-interacting protein of 120 kDa A, TIP120, TIP120A, p120 CAND1
- 基因ID
- 55832
- NCBI登录号
- NP_060918
- UniProt
- Q86VP6
- 途径
- Regulation of Actin Filament Polymerization
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