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DCLRE1C 抗体 (AA 482-495)

DCLRE1C 适用: 人 WB, IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN117935
发货至: 中国
  • 抗原 See all DCLRE1C 抗体
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    抗原表位
    • 15
    • 10
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 482-495
    适用
    • 44
    • 28
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 59
    • 1
    山羊
    克隆类型
    • 60
    多克隆
    标记
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DCLRE1C antibody is un-conjugated
    应用范围
    • 46
    • 28
    • 23
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects a band of the appropriate size in a number of different cell lines. However, it does not detect a band in cell lines that do not express ARTEMIS, such as the cell line CJ and in an hTERT line.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography using the immunizing peptide after immobilization to a solid phase.
    免疫原
    This antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C). Genename: DCLRE1C
    Top Product
    Discover our top product DCLRE1C Primary Antibody
  • 应用备注
    This antibody has been tested for use in ELISA (1: 10,000-1: 20,000), Immunohistochemistry(1: 1,000) and Western blotting (1: 500-1: 2,000). Reactivity in other immunoassays isunknown. This antibody detects a band of approximately 90 kDa (predicted molecular weight: 78 kDa).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.2 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2, with 0.01 %(w/v) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute only prior to immediate use. Avoid cycles of freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at -20 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Centrifuge product if not completely clear after standing at room temperature. This product is stable for one month at 2-8 °C as an undiluted liquid.
  • 抗原
    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
    别名
    Artemis (DCLRE1C 产品)
    别名
    artemis antibody, A-SCID antibody, DCLREC1C antibody, RS-SCID antibody, SCIDA antibody, SNM1C antibody, hSNM1C antibody, Snm1l antibody, nuclease antibody, 9930121L06Rik antibody, AI661365 antibody, Art antibody, DNA cross-link repair 1C antibody, DCLRE1C antibody, Dclre1c antibody
    背景
    Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNAPKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
    基因ID
    64421
    NCBI登录号
    NP_001029027
    UniProt
    Q96SD1
    途径
    DNA Damage Repair
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