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NFKB2 抗体 (N-Term)

NFKB2 适用: 人 WB, IP, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN116523
发货至: 中国
  • 抗原 See all NFKB2 抗体
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    抗原表位
    • 16
    • 14
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    • 11
    • 11
    • 5
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    • 1
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    • 1
    • 1
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    N-Term
    适用
    • 135
    • 96
    • 60
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    • 2
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    • 1
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    宿主
    • 134
    • 7
    克隆类型
    • 123
    • 17
    • 1
    多克隆
    标记
    • 79
    • 12
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    • 5
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    This NFKB2 antibody is un-conjugated
    应用范围
    • 86
    • 48
    • 41
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    • 16
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    • 11
    • 3
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    Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
    特异性
    Anti-Human NFKB2 p52 may react non-specifically with other proteins. Control peptide (R1011CP) will compete only with the specific reaction of antiserum with Human NFKB2 p52.
    纯化方法
    Prepared from monospecific antiserum by delipidation and defibrination.
    免疫原
    Human NFkB p52/p100 peptide corresponding to a region near the N-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
    Top Product
    Discover our top product NFKB2 Primary Antibody
  • 应用备注
    Suitable for Western blotting (1/1000), Immunoprecipitation and ELISA. Use control peptide at 1 l per l of antiserum. Recommended Dilutions: This product was assayed by immunoblot and found to bereactive against Human NFKB2 p52 at a dilution of 1: 1000 followed by reaction withPeroxidase conjugated Affinity Purified anti-Rabbit IgG [H&L] (Goat). Anti-Human NFKB2p52 is suitable for the detection by immunoblot of Human NFKB2 p52 and its precursorprotein p100. Cross reactivity with p52 from other species may occur but has not beenspecifically determined. Reactivity in supershift assays has not been determined.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    90.0 mg/mL (by Refractometry)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
  • 抗原
    NFKB2 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2))
    别名
    NFKB2 / NF-kappa-B p100/p52 (NFKB2 产品)
    别名
    NF-kappaB2 antibody, lyt antibody, p49 antibody, p49/p100 antibody, p50B antibody, p52 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 antibody, Nfkb2 antibody
    背景
    NFκB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFκB bound to IκB. NFκB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFKB1) subunits. Other identified subunits include p52 (NFKB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFκB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by an inhibitor called IκB-α. IκB-α binds to the p65 subunit, preventing nuclear localization and DNA binding. Low levels of p52 and p50 homodimers can also exist in cells.Synonyms: DNA-binding factor KBF2, H2TF1, KBF2, LYT10, Lymphocyte translocation chromosome 10, NF kappa B, NF-kB p100, NF-kB p52, Nuclear factor NF-kappa-B p100 subunit, Oncogene Lyt-10
    基因ID
    4791
    NCBI登录号
    NP_001070961
    UniProt
    Q00653
    途径
    Toll-Like Receptors Cascades
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