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CXCL1 抗体 (Biotin)

CXCL1 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN116257
发货至: 中国
  • 抗原 See all CXCL1 抗体
    CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This CXCL1 antibody is conjugated to Biotin
    应用范围
    • 71
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    Reacts with Growth Related Oncoprotein alpha.
    纯化方法
    Affinity chromatography.
    免疫原
    Highly pure (>98%) recombinant hGRO/MGSA (human GRO/MGSA).
    Top Product
    Discover our top product CXCL1 Primary Antibody
  • 应用备注
    ELISA: To detect hGRO/MGSA by direct ELISA (using 100 l/well antibody solution) thisantibody can be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthGRO/MGSA. Western Blot: To detect hGRO/MGSA by Western Blot analysis this antibody can be used ata concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hGRO/MGSA is 1.5 - 3.0 ng/lane, under eitherreducing or non-reducing conditions.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    CXCL1 (Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1))
    别名
    CXCL1 / GRO-alpha (CXCL1 产品)
    别名
    FSP antibody, GRO1 antibody, GROa antibody, MGSA antibody, MGSA-a antibody, NAP-3 antibody, SCYB1 antibody, CINC-1 antibody, Gro1 antibody, CXCL1 antibody, Sdf1 antibody, Fsp antibody, KC antibody, Mgsa antibody, N51 antibody, Scyb1 antibody, gro antibody, GRO antibody, Gro antibody, C-X-C motif chemokine ligand 1 antibody, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody, C-X-C motif chemokine ligand 12 antibody, chemokine (C-X-C motif) ligand 1 antibody, CXCL1 antibody, Cxcl1 antibody, Cxcl12 antibody, GRO1 antibody
    背景
    The GRO gene was originally identified by subtractive hybridization studies between normal and tumorigenic Chinese hamster embryo fibroblasts. The hamster cDNA was cloned and used as a probe for cloning of the human GRO cDNA. The GROalpha gene initially cloned from T24 cells and the gene in melanoma cells encoding melanoma growth stimulating protein (MGSA) are identical. Human cells contain three closely related, but distinct GRO genes: GRO alpha, GRO beta, and GRO gamma. GRO beta and GRO gamma share 93 % and 82 % identity, respectively, with GRO alpha at the nucleotide level. GROs are members of the chemokine alpha family that is characterized by the separation with one amino acid of the first two cysteine residues, C-X-C, in the amino acid sequence. The GRO gene has been mapped to chromosome 4q21. In normal cells, human mRNA GRO expression is found in foreskin fibroblasts, synovial fibroblasts, chondrocytes and osteocytes. Additionally, GRO mRNA has been detected in mammary fibroblasts, mammary epithelial cells, endothelial cells, activated monocytes, macrophages, and neutrophils. Characterization of the GROalpha receptor indicates the presence of low and high affinity receptors on human neutrophils.Synonyms: CXCL1, GRO, GRO-alpha(1-73), GRO1, GROA, Growth-regulated alpha protein, MGSA, Melanoma growth stimulatory activity, NAP-3, Neutrophil-activating protein 3, SCYB1
    基因ID
    2919
    NCBI登录号
    NP_001502
    UniProt
    P09341
    途径
    Autophagy
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