电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Resistin 抗体

RETN 适用: 人 WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN115515
发货至: 中国
  • 抗原 See all Resistin (RETN) 抗体
    Resistin (RETN)
    适用
    • 83
    • 27
    • 11
    • 7
    • 1
    • 1
    宿主
    • 83
    • 23
    • 10
    • 4
    • 3
    山羊
    克隆类型
    • 101
    • 23
    多克隆
    标记
    • 71
    • 18
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Resistin antibody is un-conjugated
    应用范围
    • 87
    • 57
    • 34
    • 14
    • 10
    • 10
    • 9
    • 9
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    The antibody recognizes human Resistin. Other species not tested.
    纯化方法
    Immunoaffinity chromatography on a column with immobilized recombinant Human Resistin
    免疫原
    Recombinant Human Resistin (Source of antigen: E. coli)
    Top Product
    Discover our top product RETN Primary Antibody
  • 应用备注
    ELISA. Western blotting.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Add 0.1 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
    缓冲液
    Lyophilized from 1 mg/mL in 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2, AZIDE FREE
    储存液
    Sodium azide
    注意事项
    Do Not Use Sodium Azide as Preservative.
    注意事项
    Avoid repeated freezing and thawing. Dilute only prior to immediate use
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 2-8 °C prior to restoration. For extended storage add glycerol to 50% and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.
  • 抗原
    Resistin (RETN)
    别名
    Resistin (RETN 产品)
    别名
    RETN antibody, ADSF antibody, FIZZ3 antibody, RETN1 antibody, RSTN antibody, XCP1 antibody, Fizz3 antibody, Rstn antibody, Xcp4 antibody, resistin antibody, RETN antibody, Retn antibody
    背景
    Resistin, a product of the RSTN gene, is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family, and is also described as ADSF (Adipose Tissue-Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone). Human resistin contains 108 amino acids as a prepeptide, and its hydrofobic signal peptide is cleaved before its secretion. Resistin circulates in human blood as a dimeric protein consisting of two 92 amino acid polypeptides, which are disulfide-linked via Cys26. Resistin may be an important link between obesity and insulin resistance. Mouse resistin, specifically produced and secreted by adipocyte, acts on skeletal muscle myocytes, hepatocytes and adipocytes themselves so that it reduces their sensitivity to insulin. Steppan et al. have suggested that resistin suppresses the ability of insulin to stimulace glucose uptake. They have also suggested that resistin is present at elevated levels in blood of obese mice, and is down regulated by fasting and antidiabetic drugs. Way et al., on the other hand, have found that resistin expression is severly suppressed in obesity and is stimulated by several antidiabetic drugs. Other studies have shown that mouse resistin increases during the differentiation of adipocytes, but it also seems to inhibit adipogenesis. In contrast, the human adipogenic differentiation is likely to be associated with a down regulation of resistin gene expression. Recent studies have shown that human resistin is expressed also in macrophages and may be a novel link between inflammation and insulin resistance.Synonyms: ADSF, Adipose tissue-specific secretory factor, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, RETN, RSTN
    基因ID
    56729
    NCBI登录号
    NP_001180303
    UniProt
    Q9HD89
    途径
    Feeding Behaviour, Smooth Muscle Cell Migration
You are here:
客服