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兔 anti-人 IgE Antibody

IHC (fro), IHC (p) Polyclonal unconjugated
产品编号 ABIN115320
发货至: 中国
  • 抗原 See all IgE products
    IgE
    适用
    • 48
    • 30
    • 10
    • 10
    • 5
    • 4
    • 2
    • 1
    宿主
    • 58
    • 18
    • 10
    • 10
    • 4
    • 1
    克隆类型
    • 66
    • 28
    多克隆
    应用范围
    • 55
    • 39
    • 30
    • 20
    • 20
    • 15
    • 12
    • 10
    • 10
    • 8
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Purified
    免疫原
    IgE isolated from the serum of a patient with IgE-myeloma.
  • 应用备注
    Immunohistochemistry on Formalin-Fixed Praffin Embedded Sections: Use at a dilution of1/50-1/500 in an ABC method (30 minutes at room temperature) Recommended Positive Control: Tonsil.

    Other applications not tested.
    Otimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -28 °C for longer.
  • 抗原
    IgE
    Abstract
    IgE 产品
    背景
    IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/mL, compared to 10 mg/mL for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.Synonyms: Immunoglobulin E human
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