Ret Proto-Oncogene 抗体 (RET) (C-Term)

Details for Product anti-RET Antibody No. ABIN115113, 供应商: Log in to see
抗原
  • c-ret
  • cret
  • etID315074.13
  • ret1
  • wu:fd13h01
  • X-ret
  • ret-A
  • xret
  • RET
  • MTC1
  • CDHF12
  • CDHR16
  • HSCR1
  • MEN2A
  • MEN2B
  • PTC
  • RET-ELE1
  • RET51
  • RET9
  • c-Ret
  • ret proto-oncogene receptor tyrosine kinase
  • ret proto-oncogene
  • ret
  • RET
  • Ret
抗原表位
C-Term
52
41
30
28
25
22
22
15
14
14
12
11
8
8
8
8
8
8
6
5
4
4
4
4
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
适用

395
117
107
9
3
2
2
2
2
1
1
1
1
1
1
1
宿主
小鼠
246
147
5
2
1
1
克隆类型 (克隆位点)
单克隆 ()
标记
This Ret Proto-Oncogene antibody is un-conjugated
17
15
15
12
12
9
9
9
8
8
8
5
5
5
5
5
5
4
4
2
2
1
1
1
1
1
1
1
1
1
1
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
274
144
93
82
65
61
27
8
6
5
4
4
3
3
1
1
选项
Supplier
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免疫原 BALB/C mice were injected with recombinant protein encoding the extreme C-terminal cytoplasmic region of the human ret oncoprotein.
克隆位点 RET01
亚型 IgG1
特异性 Reacts to Ret Oncoprotein.
Cellular Localization: Cytoplasmic.
纯化方法 Purified
别名 RET (RET Antibody 摘要)
背景 Ret proto-oncogene encodes a cell surface glycoprotein belonging to a member of the receptor tyrosine kinase family and is located on chromosome 10q11.2. Ret is observed in several regions of the central nervous system, in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain.Synonyms: C-ret, CDHF12, Cadherin family member 12, Proto-oncogene tyrosine-protein kinase receptor ret
基因ID 5979
NCBI登录号 NP_065681
UniProt P07949
研究领域 Signaling, Kinases/Phosphatases
途径 RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
应用备注 Immunohistochemistry on paraffin embedded sections: diluted of 1: 10-1: 20 in an ABC method (90 minutes at room temperature), requires hightemperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Small intestine.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
状态 Liquid
缓冲液 Sodium azide as preservative
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Ret Proto-Oncogene (RET) (C-Term) antibody (ABIN115113) Formalin fixed paraffin embedded human small intestine stained with ret oncoprotein a...
背景 Nosrat, Tomac, Hoffer, Olson: "Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs." in: Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, Vol. 115, Issue 3, pp. 410-22, 1997 (PubMed).

Williams, Rooney, Carss, Cummins, Thomas, Williams: "Analysis of the RET proto-oncogene in sporadic parathyroid adenomas." in: The Journal of pathology, Vol. 180, Issue 2, pp. 138-41, 1997 (PubMed).

Nakamura, Ishizaka, Nagao, Hara, Ishikawa: "Expression of the ret proto-oncogene product in human normal and neoplastic tissues of neural crest origin." in: The Journal of pathology, Vol. 172, Issue 3, pp. 255-60, 1994 (PubMed).

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