Thrombospondin 1 抗体 (THBS1)

Details for Product anti-THBS1 Antibody No. ABIN115004, 供应商: Log in to see
抗原
  • TMTSP
  • UNQ3010
  • THBS
  • THBS-1
  • TSP
  • TSP-1
  • TSP1
  • CRISP-2
  • CT36
  • GAPDL5
  • TPX1
  • Thbs-1
  • tbsp1
  • thrombospondin-1
  • thbs
  • thbs-1
  • tsp
  • tsp-1
  • tsp1
  • Tsp1
  • THBS1
  • Tsp-1
  • wu:fc48c03
  • si:dkey-11e23.1
  • 4833423O18Rik
  • Tmtsp
  • thrombospondin, type I, domain containing 1
  • thrombospondin 1
  • cysteine-rich secretory protein 2
  • thrombospondin, type I, domain 1
  • THSD1
  • THBS1
  • CRISP2
  • Thsd1
  • Thbs1
  • thbs1
  • LOC100230636
适用
哺乳动物
153
63
59
25
18
18
16
16
3
3
1
1
1
宿主
小鼠
129
43
30
克隆类型 (克隆位点)
单克隆 ()
标记
This Thrombospondin 1 antibody is un-conjugated
28
16
9
4
4
3
1
应用范围
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
158
103
56
37
33
32
17
17
10
8
4
4
3
3
2
2
2
2
2
2
2
2
选项
Supplier
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Supplier Product No.
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免疫原 BALB/C mice were injected with reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated platelets.
克隆位点 A6-1
亚型 IgG1
特异性 This antibody is specific to 450 kDa protein (non-reduced) and 170 to 180 kDa (reduced) form of Thrombospondin.
Cellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum
纯化方法 Purified
别名 Thrombospondin-1 (THBS1) (THBS1 Antibody 摘要)
背景 Thrombospondin is a protein from platelet a granules. It is secreted at sites of platelet activation and aggregation and is involved in the differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells.Synonyms: TSP, TSP1
基因ID 7057
NCBI登录号 NP_003237
UniProt P07996
研究领域 Extracellular Matrix
途径 Autophagy
应用备注 Immunofluorescence. Immunoprecipitation. Western Blot. Immunohistochemistry on paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30 minutes at room temperature). Formalin fixedparaffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Tonsil
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用
状态 Liquid
缓冲液 Sodium azide as preservative
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
厂商提供的图像
Immunohistochemistry (IHC) image for anti-Thrombospondin 1 (THBS1) antibody (ABIN115004) Formalin fixed paraffin embedded human tonsil stained with Thrombospondin antibody. A...
背景 Galvin, Vance, Dixit, Fink, Frazier: "Interaction of human thrombospondin with types I-V collagen: direct binding and electron microscopy." in: The Journal of cell biology, Vol. 104, Issue 5, pp. 1413-22, 1987 (PubMed).

Dixit, Galvin, ORourke, Frazier: "Monoclonal antibodies that recognize calcium-dependent structures of human thrombospondin. Characterization and mapping of their epitopes." in: The Journal of biological chemistry, Vol. 261, Issue 4, pp. 1962-8, 1986 (PubMed).

Dixit, Haverstick, ORourke, Hennessy, Grant, Santoro, Frazier: "Effects of anti-thrombospondin monoclonal antibodies on the agglutination of erythrocytes and fixed, activated platelets by purified thrombospondin." in: Biochemistry, Vol. 24, Issue 16, pp. 4270-5, 1985 (PubMed).

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