Osteoprotegerin 抗体
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- 抗原 See all Osteoprotegerin (TNFRSF11B) 抗体
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Osteoprotegerin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- The antibody recognizes human Osteoprotegerin. Other species not tested.
- 纯化方法
- Affinity chromatography on protein G
- 免疫原
- Recombinant human Osteoprotegerin (OPG Fc Chimera) produced in E. coli.
- 克隆位点
- OPG-01
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF11B Primary Antibody
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- 应用备注
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ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 溶解方式
- Restore with 0.1 mL of deionized water. Let the pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
- 浓度
- 1.0 mg/mL
- 缓冲液
- 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2
- 注意事项
- Avoid repeated freezing and thawing. Do Not Freeze working dilutions.
- 储存条件
- -20 °C
- 储存方法
- Stock solution or aliquots thereof can be kept frozen at -20 °C.
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- 抗原
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- 别名
- Osteoprotegerin / TNFRSF11B (TNFRSF11B 产品)
- 别名
- CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
- 物质类
- Chemical
- 背景
- Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
- 基因ID
- 4982
- NCBI登录号
- NP_002537
- UniProt
- O00300
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