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ITM2B 抗体

ITM2B 适用: 人 IHC (fro) 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN113338
发货至: 中国
  • 抗原 See all ITM2B 抗体
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    适用
    • 26
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    宿主
    • 32
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    小鸡
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 18
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    • 2
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    This ITM2B antibody is un-conjugated
    应用范围
    • 26
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    • 3
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    Immunohistochemistry (Frozen Sections) (IHC (fro))
    序列
    CSRTVKKNII EEN
    特异性
    The antibody recognizes the typical amyloid deposits in brains of patients suffering from the disease. This antibody has been developed against the carboxy terminal extracellular sequence of the mutated BRI protein.
    纯化方法
    Affinity chromatography.
    免疫原
    Peptide coupled to carrier protein.
    Top Product
    Discover our top product ITM2B Primary Antibody
  • 应用备注
    Suitable for Immunohistochemistry on frozen sections. Suggested positive control: pathological brain sections. (Not recommended in Western blots).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg /ml
    缓冲液
    PBS, pH 7.2, containing 0.09 % sodium azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2-8 °C (Lyophilized) or reconstituted in small aliquots at -20 °C.
  • 抗原
    ITM2B (Integral Membrane Protein 2B (ITM2B))
    别名
    ITM2B (ITM2B 产品)
    别名
    ABRI antibody, BRI antibody, BRI2 antibody, BRICD2B antibody, E25B antibody, E3-16 antibody, FBD antibody, imBRI2 antibody, AI256040 antibody, Bri antibody, Bri2 antibody, Bricd2b antibody, D14Sel6 antibody, E25BMM antibody, itm2b antibody, zgc:55770 antibody, zgc:85688 antibody, wu:fc05f02 antibody, MGC52745 antibody, MGC76131 antibody, ITM2B antibody, itm2bl antibody, wu:fb94b03 antibody, zgc:64142 antibody, integral membrane protein 2B antibody, integral membrane protein 2Ba antibody, integral membrane protein 2B L homeolog antibody, integral membrane protein 2b antibody, integral membrane protein 2Bb antibody, ITM2B antibody, Itm2b antibody, itm2ba antibody, itm2b.L antibody, itm2b antibody, itm2bb antibody
    背景
    The mutated BRI protein (ITM2B) was identified in patients with familial British dementia. The unusual 277 residue precursor protein releases a 34-residue amyloidogenic peptide by the action of the protease furin, leading to the deposition of a protein fragment that seems to be involved in the pathogenesis of familial British dementia.Synonyms: BRI, BRI2, ITM2B, Integral membrane protein 2B, Transmembrane protein BRI
    基因ID
    9445
    NCBI登录号
    NP_068839
    UniProt
    Q9Y287
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