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CDH6 抗体 (Extracellular Domain)

CDH6 适用: 人 WB, IHC (p), IF, IHC (fro) 宿主: 小鼠 Monoclonal 2B6 unconjugated
产品编号 ABIN112365
发货至: 中国
  • 抗原 See all CDH6 抗体
    CDH6 (K-Cadherin (CDH6))
    抗原表位
    • 16
    • 11
    • 9
    • 8
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 65
    • 9
    • 9
    • 5
    • 1
    宿主
    • 60
    • 3
    • 2
    小鼠
    克隆类型
    • 62
    • 3
    单克隆
    标记
    • 26
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDH6 antibody is un-conjugated
    应用范围
    • 64
    • 36
    • 35
    • 32
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Clone 2B6 recognizes the extracellular domain of Cadherin-6.
    交叉反应 (详细)
    Species reactivity (tested):Human, Rat.
    纯化方法
    Purified
    免疫原
    Affinity purified extracellular domain of human cadherin-6-GST fusion protein
    克隆位点
    2B6
    亚型
    IgG1
    Top Product
    Discover our top product CDH6 Primary Antibody
  • 应用备注
    Immunoblotting (1: 25 - 1: 250). Immunocytochemistry. Immunohistochemistry on frozen sections when using a PBS buffer containing 0.1 mMCaCl2 and 0.1 mM MgCl2. Recommended range is 1: 25 - 1: 50 for immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CDH6 (K-Cadherin (CDH6))
    别名
    Cadherin-6 (CDH6 产品)
    背景
    Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. The cadherins generally contain five extracellular repeats, a transmembrane domain and a cytoplasmic tail that binds to the catenin family of cytoskeletal anchoring proteins which also function as signal transducers. The extracellular domains are responsible for the specificity of homophilic interactions between cells expressing the same cadherin. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4). Kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. Cadherin-6 is expressed in the proximal tubule epithelium of the kidney from which most renal cell carcinomas are derived.Synonyms: CDH6, Cadherin K, K-Cadherin, Kidney cadherin
    基因ID
    1004
    NCBI登录号
    NP_004923
    UniProt
    P55285
    途径
    Cell-Cell Junction Organization
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