电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NEFH 抗体

NEFH 适用: 人, 大鼠, 小鼠, 小鸡, Cow, 豚鼠, 兔, 犬, 绵羊, 非洲爪蟾 WB, IHC (p), IF, IHC (fro) 宿主: 小鼠 Monoclonal RNF402 unconjugated
产品编号 ABIN112360
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    适用
    • 108
    • 81
    • 63
    • 47
    • 28
    • 27
    • 11
    • 11
    • 8
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    人, 大鼠, 小鼠, 小鸡, Cow, 豚鼠, 兔, 犬, 绵羊, 非洲爪蟾
    宿主
    • 66
    • 56
    • 10
    小鼠
    克隆类型
    • 82
    • 50
    单克隆
    标记
    • 89
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFH antibody is un-conjugated
    应用范围
    • 89
    • 44
    • 37
    • 29
    • 26
    • 23
    • 23
    • 16
    • 14
    • 13
    • 13
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    RNF402 reacts with both the phosphorylated and non-phosphorylated isoforms of the 200 kDa Neurofilament protein. Reacts with Human, Rat, Rabbit, Dog, Hamster, Chicken, Mouse, Cow, Monkey, Sheep, Guinea Pig and Xenopus.
    纯化方法
    Purified
    免疫原
    Neurofilament preparation of calf brain tissue.
    克隆位点
    RNF402
    亚型
    IgM
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    ImmunoblottingImmunohistochemistry on Frozen and Paraffin Embedded Tissues. Recommended Dilutions: 1/10-1/100 for Immunohistochemistry with avidin biotinylatedHorseradish Peroxidase complex (ABC) as detection reagent, and 1/25-1/250 forImmunoblotting applications.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized at 2 - 8 °C and reconstituted at -20 °C.
  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    Neurofilament H (200 kD) (NEFH 产品)
    别名
    NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
    背景
    Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble. All three NF proteins can be detected by immunohistochemical methods at day 9 or 10 after gestation in the mouse embryo. Although IFPs of the neurofilament type are normally restricted to neurons, there are reports on their expression in non-neuronal cells as well. For example, in heart conduction myocytes NF proteins are expressed together with desmin. In tumorpathology ganglioneuroblastomas and some of the other neuroblastomas are strongly positive with the neurofilament antisera. Also, some neuro-endocrine malignancies may show NF positivity. In cell cultures of neural tissues the neurofilament antibodies can monitor in vitro differentiation.Synonyms: (Neuronal Marker), 200 kDa neurofilament protein, KIAA0845, NEFH, NF-H, NFH, Neurofilament triplet H protein, heavy polypeptide
    基因ID
    4744
    NCBI登录号
    NP_066554
    UniProt
    P12036
You are here:
客服