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ICAM1 抗体 (Biotin)

ICAM1 适用: 人 WB, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 1304 Biotin
产品编号 ABIN111935
发货至: 中国
  • 抗原 See all ICAM1 抗体
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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    小鼠
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    单克隆
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    This ICAM1 antibody is conjugated to Biotin
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein A Chromatography.
    免疫原
    Cultured Human endothelial cells
    克隆位点
    1304
    亚型
    IgG2a
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • 应用备注
    Immunohistochemistry on Frozen Sections: 0.25 μg/mL (1/800). Immunohistochemistry on Paraffin Sections: 2 μg/mL (1/100). Proteinase K pretreatmentfor antigen retrieval is recommended. Suggested Positive Control: Human tonsil. Has been described to work in FACS and Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 0.5 mL distilled water.
    浓度
    0.2 mg/mL
    缓冲液
    Stock Solution contains PBS, pH 7.2 with 0.01 % Thimerosal as preservative and 1 % BSA as stabilizer.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted Prior to and following reconstitution at 2-8 °C. DO NOT FREEZE.
  • 抗原
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    别名
    CD54 / ICAM1 (ICAM1 产品)
    别名
    BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
    物质类
    Viral Protein
    背景
    ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    基因ID
    9606
    UniProt
    P05362
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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