RAGE 抗体 (Middle Region)
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- 抗原 See all RAGE (AGER) 抗体
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAGE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- This antibody detects RAGE / AGER. No cross reactivity with other proteins.
- 交叉反应 （详细）
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat. - 纯化方法
- Immunoaffinity Chromatography
- 免疫原
- Synthetic peptide corresponding to a sequence mapping in the middle region of Human advanced glycosylation end-product-specific receptor(RAGE), different from the related Mouse and Rat sequences by two amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product AGER Primary Antibody
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anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 180-402) antibody
AGER 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 1-404) antibodyAGER 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 151-250) antibodyAGER 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IP, IF (cc), ICC, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-274) antibodyAGER 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 23-404) antibodyAGER 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 91-120), (N-Term) antibodyAGER 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 76-104) antibodyAGER 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) antibodyAGER 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (N-Term) antibodyAGER 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (C-Term) antibodyAGER 适用: 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 ug/ml.
- 缓冲液
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- 别名
- RAGE / AGER (AGER 产品)
- 别名
- RAGE antibody, AGER antibody, advanced glycosylation end-product specific receptor antibody, advanced glycosylation end product-specific receptor antibody, MAPK/MAK/MRK overlapping kinase antibody, AGER antibody, Ager antibody, LOC719012 antibody
- 背景
- The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimer's disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes, and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment.Synonyms: Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products
- 基因ID
- 177
- NCBI登录号
- NP_001127
- UniProt
- Q15109
- 途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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